Results 81 to 90 of about 98,475 (290)

Shared Responsibilities for Nuclear Disarmament: A Global Debate [PDF]

, 2010
Presents Sagan's 2009 paper calling for rethinking the balance of responsibilities and the relationship between articles in the Nuclear Non-Proliferation Treaty with seven response papers by international scholars about how to pursue nuclear ...
Achilles Zaluar, Harald Muller, James M. Acton, Jayantha Dhanapala, Mohamed I. Shaker, Mustafa Kibaroglu, Scott D. Sagan, Yukio Satoh   +7 more
core  

Engineering exosomal cargo loading via endogenous molecular pathways: Strategies to enhance therapeutic potential

Interdisciplinary Medicine, EarlyView.
This review illustrates how scientists engineer exosomes by hijacking the cell's own cargo‐sorting machinery. These strategies efficiently load therapeutic molecules into natural vesicles, creating powerful next‐generation drug delivery systems (Created with BioGDP.com).
Huanrong Zhu, Chenning Zhang, Shihan Ma, Zhanxue Xu, Cailing Liang, Fang Cheng, Hongbo Chen   +6 more
wiley   +1 more source

Molecular dynamics simulations of oleuropein diffusion in chitosan‐based nanoparticles

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND This study explores the diffusion mechanisms of oleuropein (OLE), a promising polyphenolic compound, within chitosan‐based nanoparticles using molecular dynamics simulations. Chitosan nanoparticles serve as drug delivery carriers, leveraging biocompatibility and tunable release properties influenced by environmental factors such as ...
Bernardino Tirri, Andrea Lorenzoni, Francesco Mercuri, Pietro Calandra   +3 more
wiley   +1 more source

Microscopic dynamics of charge separation at the aqueous electrochemical interface

, 2017
We have used molecular simulation and methods of importance sampling to study the thermodynamics and kinetics of ionic charge separation at a liquid water-metal interface.
Kattirtzi, John A., Limmer, David T., Willard, Adam P.   +2 more
core   +1 more source

Metabolic Dysfunction‐Associated Steatotic Liver Disease and Obesity: Pathogenesis, Diagnostics, Risk Stratification, and Therapeutic Approach

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as the most prevalent chronic liver disease worldwide, closely linked to the global rising incidence of obesity and metabolic syndrome. This review synthesizes current evidence on the pathogenesis, gut–liver axis, and multidisciplinary management of MASLD within the ...
Beom Kyung Kim
wiley   +1 more source

Thermal-Hydraulic System Codes in Nulcear Reactor Safety and Qualification Procedures

Science and Technology of Nuclear Installations, 2008
In the last four decades, large efforts have been undertaken to provide reliable thermal-hydraulic system codes for the analyses of transients and accidents in nuclear power plants. Whereas the first system codes, developed at the beginning of the 1970s,
Alessandro Petruzzi, Francesco D'Auria
doaj   +1 more source

First 20 Years of Orbitrap Mass Spectrometry as the Mainstream Analytical Technique

Mass Spectrometry Reviews, EarlyView.
ABSTRACT This review traces the first 20 years of Orbitrap mass spectrometry as a mainstream high‑resolution and accurate‑mass (HR/AM) technology. It outlines the historical development of the Orbitrap analyzer, the evolution of major instrument families, and the key technological innovations that enabled its widespread adoption. Particular emphasis is
Alexander Makarov
wiley   +1 more source

Plea for Defect Chemistry: The Fundamental Role of the Chemically Excited States in Solid‐State Chemistry and Beyond

Zeitschrift für anorganische und allgemeine Chemie, EarlyView.
In solids, the point defects take the role that in water is held by H3O+, OH−, and solutes. While the chemical ground structure (crystallographic structure) plays the role of the matrix, it is the chemically excited states (dissociation, disorder) that breathe life into the matter.
Joachim Maier
wiley   +1 more source

Impact of PET/CT Imaging with FDG in Locally Advanced Cervical Carcinoma—A Literature Review

Current Oncology
Positron emission tomography (PET) and computed tomography (CT) have evolved as a pivotal diagnostic modality in the field of oncology. With its increasing application in staging and ready availability, it becomes imperative for committed radiation ...
Ottó Molnar, Oreste Mihai Straciuc, Simona Mihuțiu, Liviu Lazăr   +3 more
doaj   +1 more source

A urinary metabolite constellation to detect acute rejection in kidney allografts

EBioMedicine, 2019
Background: To validate a novel method for post-transplant surveillance to detect kidney allograft rejection via a characteristic constellation of the urine metabolites alanine, citrate, lactate, and urea investigated by nuclear magnetic resonance (NMR ...
Miriam C. Banas, Sindy Neumann, Philipp Pagel, Franz Josef Putz, Bernhard K. Krämer, Georg A. Böhmig, Johannes Eiglsperger, Eric Schiffer, Petra Ruemmele, Bernhard Banas   +9 more
doaj   +1 more source