Results 111 to 120 of about 466,448 (222)
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
The independence-dependence paradox: stability dilemmas in south [PDF]
, 2003 Has a new era of detente and stability emerged in South Asia five years after India and Pakistan first openly tested nuclear weapons? In the process, have India and Pakistan effectively demonstrated the value of nuclear weapons in deterring war ...
Khan, Feroz Hassan
core
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Development and Validation of Anxiety Due to Nuclear War Threat Scale
Psychological TopicsAnxiety is a common reaction to the threat of nuclear war, and there is a need for a reliable and valid measure to assess it. Existing questionnaires on the specific anxiety due to the danger of nuclear war only measure some of the four clusters of ...
Vicko Ćudina +4 more
doaj +2 more sources
Social Medicine, 2012 This article reviews the beginnings and history of the physicians’ antinuclear movement. The role of Victor W. Sidel, MD, is described, particularly his involvement with Physicians for Social Responsibility (PSR) and International Physicians for the ...
Sidney Alexander
doaj
Вестник войск РХБ защитыCurrently, there are practically no people left who have seen the consequences of the use of nuclear weapons. This is the reason for certain frivolous statements about the advisability of using tactical nuclear weapons to solve certain tactical problems.
M. V. Supotnitskiy
doaj +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Humanitarian and public health efforts are needed to eradicate nuclear weapons
Australian and New Zealand Journal of Public Health, 2012 Tilman Ruff, Ira Helfand
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A \u3ci\u3eDr. Strangelove\u3c/i\u3e Situation : Nuclear Anxiety, Presidential Fallibility, and the Twenty-Fifth Amendment [PDF]
, 2017 This Article is a revisionist history of the ratification of the Twenty-Fifth Amendment, which establishes procedures for remedying a vice presidential vacancy and for addressing presidential inability.
Lubot, Rebecca C.
core +1 more source