Results 111 to 120 of about 3,326,409 (352)
Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients
Molecular Oncology, EarlyView.Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha +6 more
wiley +1 more source
Risk Mathematics and Quantum Games on Quantum Risk Structures - A Nuclear War Scenario Game [PDF]
arXiv, 2012 Quantum game theory is combined with risk mathematics' formalism to provide an approach to evolutionary scenario analysis. The formalism is addressed in its general form and is then applied to an extreme risks modelling case, to model a coevolving dynamical web of systemic situations representing the evolution of the regional tensions between two ...
arxiv
Global Zero: The new old agenda [PDF]
, 2009 The project of abolishing all nuclear weapons has been given fresh impetus but the old questions remain. Having regard to the manifold problems of definition and verification, is 'Global Zero' realistic in a world in which proliferation seems more likely
Smith, Ron C.
core +1 more source
A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini +11 more
wiley +1 more source
Molecular Oncology, EarlyView.This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke +12 more
wiley +1 more source
Nuclear Deterrence: A complete failure at Kargil [PDF]
, 2015 There is a perception since long that the nuclear weapon states cannot opt for war against each other. The proponents of nuclear deterrence quote the example of the United States and Soviet Union to strengthen their view point that the two major world ...
Leghari, Farooque Ahmed +1 more
core +1 more source
, 2022 Because of its part in the nation\u27s nuclear arsenal, in a movie depicting nuclear war, and in providing an American President, Kansas\u27s Cold War rol was among the nations most ...
Brewer, Landry
core +1 more source
Molecular Oncology, EarlyView.We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić +31 more
wiley +1 more source
Molecular Oncology, EarlyView.This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou +13 more
wiley +1 more source
Methodological Themes and Variations [PDF]
, 1989 The future of civilization, perhaps of the human race, hinges on our ability to avoid nuclear war. This point has been made so repeatedly and occasionally so eloquently that it needs no amplification here (Dyson, 1984; Katz, 1982; Institute of Medicine ...
Tetlock, Philip E
core +1 more source