Results 141 to 150 of about 3,326,409 (352)

Cystatin A promotes the antitumor activity of T helper type 1 cells and dendritic cells in murine models of pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Pancreatic ductal adenocarcinoma (PDAC) is a disease with very poor prognosis due to therapeutic limitations. We investigated the antitumor effects of cystatin A (CSTA) in PDAC murine models. We are first to confirm that CSTA enhances T helper type 1‐mediated antitumor effects through promotion of dendritic cells and M1 macrophage activity. CSTA can be
Alessandro Nasti   +8 more
wiley   +1 more source

Factors modulating 99mTc‐MAA planar lung dosimetry for 90Y radioembolization

open access: yesJournal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Purpose To investigate the accuracy and biases of predicted lung shunt fraction (LSF) and lung dose (LD) calculations via 99mTc‐macro‐aggregated albumin (99mTc‐MAA) planar imaging for treatment planning of 90Y‐microsphere radioembolization.
Benjamin P. Lopez   +4 more
wiley   +1 more source

A reel nightmare exposed : a study of the cultural significance of Stanley Kubrick's Dr. Strangelove (1964) [PDF]

open access: yes, 2003
Over the past forty years, Stanley Kubrick’s Dr. Strangelove, or: How I Learned to Stop Worrying and Love the Bomb (1964) has become an icon that suggests the dangers of nuclear holocaust.
NC DOCKS at The University of North Carolina Wilmington
core   +6 more sources

Photographed by the Earth: War and media in light of nuclear events

open access: yesNECSUS, 2014
This article charts a media historical relation between radiation and celluloid film, ranging from the downwind 1956 production of The Conqueror to early scientific imaging practices, war photography, war documentaries, military industrial film, and ...
Thomas Pringle
doaj   +1 more source

Julian Schwinger (1918-1994) [PDF]

open access: yesarXiv, 2006
Julian Schwinger's influence on Twentieth Century science is profound and pervasive. Of course, he is most famous for his renormalization theory of quantum electrodynamics, for which he shared the Nobel Prize with Richard Feynman and Sin-itiro Tomonaga.
arxiv  

Etoposide‐induced cancer cell death: roles of mitochondrial VDAC1 and calpain, and resistance mechanisms

open access: yesMolecular Oncology, EarlyView.
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita   +1 more
wiley   +1 more source

A case of Beauveria bassiana keratitis confirmed by internal transcribed spacer and LSU rDNA D1–D2 sequencing

open access: yesNew Microbes and New Infections, EarlyView., 2014
Abstract We describe a case of fungal keratitis due to Beauveria bassiana in a farmer with Fuchs' dystrophy, treated with amphotericin B. Surgery with penetrating keratoplasty was necessary to resolve the lesions. Susceptibility testing and molecular sequencing permitted the identification and treatment of this rare aetiological agent of invasive ...
M. Ligozzi   +8 more
wiley   +1 more source

AAPM Task Group 298: Recommendations on certificate program/alternative pathway candidate education and training

open access: yesJournal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Entry into the field of clinical medical physics is most commonly accomplished through the completion of a Commission on Accreditation of Medical Physics Educational Programs (CAMPEP)‐accredited graduate and residency program. To allow a mechanism to bring valuable expertise from other disciplines into clinical practice in medical physics, an “
Joann I. Prisciandaro   +6 more
wiley   +1 more source

Highlights from BNL and RHIC 2017 [PDF]

open access: yesarXiv, 2018
Highlights of news from Brookhaven National Laboratory (BNL) and results from the Relativistic Heavy Ion Collider (RHIC) in the period July 2016-2017 are presented. 2017 was the 70th birthday of Brookhaven National Laboratory which was built starting in 1947 on Camp Upton, a military base in 1917 for World War I and in September 1944 for World War II ...
arxiv  

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

open access: yesMolecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi   +5 more
wiley   +1 more source

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