Results 141 to 150 of about 48,980 (246)

The Second Nuclear Age,

open access: yes, 2018
Readers of Colin Gray’s earlier works will not be disappointed by this new book, nor will his critics be surprised by his conclusions. Gray argues that the end of the Cold War does not mean that nuclear weapons can be eliminated or forgotten.
Quester, George H.
core  

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

Nuclear Terrorism and the Escalation of International Conflict

open access: yes, 2018
Terrorism in the nuclear era raises the distinctly unpleasant and highly dangerous possibility of the use of a nuclear device by terrorists. Such an incident would be serious enough by itself, but its effect could very well produce an extraordinarily ...
Frank, Forrest R.
core  

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Pakistan\u27s Nuclear Future: Worries Beyond War

open access: yes, 2008
This book, completed just before Pakistani President Musharraf imposed a state of emergency in November 2007, reflects research that the Nonproliferation Policy Education Center commissioned over the last 2 years.
Sokolski, Henry D., Mr.
core  

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

NATO and Metaphors: The Nuclear Threshold

open access: yes, 2018
Ever since the development of nuclear weapons their employment has been a major concern of military planners. Fortunately, we have had no practical experience with their use.
Norton, Augustus R.
core  

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

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