Results 1 to 10 of about 130 (124)
Ядерна фізика та енергетика, 2022 A brief overview of data of automated temperature monitoring systems at the periphery of nuclearly hazardous clusters of fuel-containing materials (FCM NHC) and analytical materials regarding the study of its dynamics at various monitoring points before ...
O. V. Mykhailov +3 more
doaj +3 more sources
Results of analysis of temperature monitoring data around the nuclearly hazardous cluster of fuel-containing materials in the sub-reactor room 305/2 of the "Shelter" object, inside and outside the new safe confinement [PDF]
Ядерна фізика та енергетикаThe results of the analysis of temperature monitoring data were obtained using the information and measuring system (IMS) "Finish" (1991 - 2015) and expert research system, new safe confinement (NSC) integrated control system in the main volume (MV ...
O. V. Mykhailov +2 more
doaj +3 more sources
Analysis of long-term monitoring data around the area of localization of nuclear-hazardous clusters in the "Shelter" Object [PDF]
Ядерна фізика та енергетикаThe results of a comprehensive analysis of neutron flux density (NFD), gamma-radiation exposure dose rate (GDR), dynamics of concrete temperature and air humidity in the vicinity of nuclearly hazardous fuel-containing material cluster (NHC) in room 305/2
O. V. Mykhailov +2 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source