Results 121 to 130 of about 238,006 (379)

Annexin A13 Protects Against Acute Kidney Injury by Inactivating TGF‐β/Smad3 Signaling

open access: yesAdvanced Science, EarlyView.
ANXA13 is negatively regulated by Smad3 and exerts its protective role in AKI by inactivating TGF‐β/Smad3 signaling and Smad3‐p21 cell cycle arrest pathway through binding to TβRI, inhibiting the interaction between TβRI and TβRII, thereby suppressing TβRI phosporylation.
Jiaxiao Li   +12 more
wiley   +1 more source

CCDC41 Drives Oocyte Meiotic Progression by Promoting Rab11a/Rab7‐Positive Vesicle Fusion with Target Membranes

open access: yesAdvanced Science, EarlyView.
CCDC41 is essential for meiotic maturation in mouse oocytes through regulating Rab7‐positive endosomes fusion with lysosomes and Rab11a‐positive vesicle fusion with the plasma membrane. Abstract Coiled‐coil domain‐containing protein 41 (CCDC41), a core component of centriolar distal appendages involved in centriole assembly and ciliary vesicle docking,
Ying Tian   +12 more
wiley   +1 more source

Bisphenol B Exposure Induces Miscarriage by Suppressing Migration/Invasion and Migrasome Formation

open access: yesAdvanced Science, EarlyView.
BPB (Bisphenol B) exposure up‐regulates ER (estrogen receptor) levels, enhances its interactions with the lnc‐HZ04 promoter region, and thus promotes ER‐mediated lnc‐HZ04 transcription. Subsequently, lnc‐HZ04 suppresses TCF4 (transcription factor 4)‐mediated PKCA (protein kinase C alpha) transcription and subsequently suppresses migration/invasion and ...
Wenxin Huang   +13 more
wiley   +1 more source

Droplet desorption modes at high heat flux

open access: yesEPJ Web of Conferences, 2019
Nonisothermal droplet desorption of aqueous salt solution H2O/LiBr during nucleate boiling was studied experimentally. A droplet was placed on a horizontal heated wall. The initial concentration of salt C0 = 25 %.
Misyura Sergey, Meleshkin Anton
doaj   +1 more source

Multifactoring concept – A key to investigation of forced-eoiling in microsystems [PDF]

open access: yes, 2009
This paper was presented at the 2nd Micro and Nano Flows Conference (MNF2009), which was held at Brunel University, West London, UK. The conference was organised by Brunel University and supported by the Institution of Mechanical Engineers, IPEM, the ...
2nd Micro and Nano Flows Conference (MNF2009)   +1 more
core  

Oscillate Boiling from Electrical Microheaters

open access: yes, 2018
Oscillate boiling offers excellent heat transfer at temperatures above the Leidenfrost temperature. Here we realize an electrical microheater with an integrated thermal probe and resolve the thermal cycle during the high-frequency bubble oscillations ...
Hu, Liangxing   +3 more
core   +1 more source

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

open access: yesAdvanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou   +10 more
wiley   +1 more source

Nucleate Pool Boiling Heat Transfer Characteristics of Refrigerant/Oil Mixture with Carbon Nanotubes

open access: yesZhileng xuebao, 2011
Influence of carbon nanotubes (CNTs) on nucleate pool boiling heat transfer characteristics of refrigerant-oil mixture was investigated experimentally. Four types of CNTs with the outside diameters from 15 nm to 80 nm and the lengths from 1.5 μm to 10 μm
Zhuang Dawei   +4 more
doaj  

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