Results 31 to 40 of about 1,974 (265)

Nucleate Boiling in Microchannels

open access: yesJournal of Heat Transfer, 2005
Dong Liu, Poh-Seng Lee and Suresh V. Garimella Purdue University, West Lafayette, Indiana 47907-2088 An understanding of bubble motion and evolution during nucleate boiling is necessary for the analysis of convective heat transfer rates in microchannels.
Liu, D., Lee, P.S., Garimella, S V
openaire   +2 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Experimental studies o

open access: yesAin Shams Engineering Journal, 2014
Experimental investigations on the influences of different contaminants to deionized water have been conducted under the sub-cooled flow boiling heat transfer inside the vertical annulus.
Mohammad Mohsen Sarafraz   +1 more
doaj   +1 more source

Heat Transfer of Water Flow Boiling in Nanostructured Open Microchannels

open access: yesEnergies, 2023
In recent years, the open microchannel has drawn increasing interest, but severe local dryout limited the heat transfer capability of flow boiling. It was anticipated that nanostructures with exceptional capillary wicking abilities would overcome this ...
Liaofei Yin   +4 more
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

Magnesium‐Based Transient Bioelectronics, Bio‐Optics and Bio‐Scaffolds

open access: yesAdvanced Functional Materials, EarlyView.
This paper reviews the state of the art and recent advances in magnesium‐based thin‐film, foils, and scaffolds for applications in transient bio‐optics, bioelectronics and tissue engineering. The design principles, fabrication methods, material properties, and integration strategies are discussed in detail.
Massimo Mariello, Yves Leterrier
wiley   +1 more source

Experimental determination of the induction period for the onset of intensive boiling of a subcooled water flow under conditions of unsteady heat release [PDF]

open access: yesE3S Web of Conferences, 2019
This paper studies prediction of the boiling crisis onset under conditions of the rapid temperature growth of the heat releasing surface washed by a water flow subcooled to the saturation temperature. We obtained experimental data on time delay for rapid
Safarov A., Levin A.
doaj   +1 more source

Experimental Flow Boiling Study of R245a at High Reduced Pressures in a Large Diameter Horizontal Tube

open access: yesEnergies, 2022
Evaporators used in organic Rankine cycles (ORC) are designed using existing flow boiling correlations that are mainly based on HVAC&R data. However, the ORC evaporators employed in the industry typically have larger diameters and operational conditions ...
Alihan Kaya   +2 more
doaj   +1 more source

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