Results 201 to 210 of about 8,087 (328)

Elevated TRIM25 Impairs Poly (ADP‐ribose) Metabolism via PARG Degradation and Mediates Compression‐Induced Intervertebral Disc Degeneration

Advanced Science, Volume 13, Issue 25, 4 May 2026.
TRIM25 acts as a multifunctional hub driving intervertebral disc degeneration under mechanical stress. Mechanical compression significantly upregulates TRIM25 expression, establishing it as a key E3 ubiquitin ligase platform. TRIM25 targets PARG and Ku80 via distinct molecular interfaces, triggering their ubiquitination and degradation.
Zhangrong Cheng, Haiyang Gao, Wenbo Wu, Pengzhi Shi, Xianglong Chen, Zimu Yu, Wang Wu, Kangcheng Zhao, Cao Yang, Yukun Zhang   +9 more
wiley   +1 more source

Sustained and Enhanced Nucleate Boiling Using Hierarchical Architectures at Large Superheats. [PDF]

Exploration (Beijing)
Wang JX, Wang H, Salmean C, Cui B, Zhong ML, Mao Y, Li JX, Yao S.   +7 more
europepmc   +1 more source

Nanosecond Laser-Textured Copper Surfaces Hydrophobized with Self-Assembled Monolayers for Enhanced Pool Boiling Heat Transfer. [PDF]

Nanomaterials (Basel), 2022
Može M, Zupančič M, Steinbücher M, Golobič I, Gjerkeš H.   +4 more
europepmc   +1 more source

Glutamine Deprivation Triggers Tribbles Homolog 3 Dependent G‐Quadruplex Resolution to Maintain DNA Repair and Tumor Survival

Advanced Science, Volume 13, Issue 27, 13 May 2026.
Glutamine deprivation triggers transient DNA damage yet activates adaptive repair in hepatocellular carcinoma cells. We identify TRIB3 as a stress‐induced nuclear scaffold that associates with DDX5 and G‐quadruplex DNA atBRCA1 andRAD51AP1 promoters. TRIB3 loss increases G4 accumulation, suppresses HR gene transcription, elevates γ‐H2A.X, and sensitizes
Qiang Ji, Xuedan Sun, Zhangran Sun, Mengfan Li, Xinyu Cheng, Shuai Tian, Rick F. Thorne, Jinming Li, Guangzhi Liu, Mian Wu, Xiaoying Liu   +10 more
wiley   +1 more source

2D Trefftz method in identification of flow boiling heat transfer coefficient in horizontal minichannel. [PDF]

Sci Rep
Grabowski M, Hożejowska S, Pawińska A, Poniewski ME.   +3 more
europepmc   +1 more source

Closure to “Discussion of ‘Effects of Surface Conditions on Nucleate Pool Boiling of Sodium’” (1966, ASME J. Heat Transfer, 88, p. 204) [PDF]

, 1966
P. J. Marto, W. M. Rohsenow
openalex   +1 more source

Adhesion‐Related Macrophages Regulate Metabolic Homeostasis Through CAV‐1 Dependency

Advanced Science, Volume 13, Issue 26, 8 May 2026.
Adipose tissue harbors a distinct macrophage subpopulation, termed adhesion‐related macrophages (ARMs), which stably adhere to adipocytes. In obesity, ARMs represent the major expanding macrophage subset. They acquire material from adipocytes and rely on Caveolin‐1 for sustained lipid handling.
Wanyu Hu, Xiyan Liao, Limin Xie, Xiaoxiao Sun, Luodi Jing, Qin Zeng, Hongwei Jiang, Haowei Zhang, Lei Li, Fanqi Wang, Dandan Wang, Ying Mei, Yujin Din, Jianfeng Song, Wufuer Aini, Hui Zhou, Wanqin Xie, Helong Dai, Wei Liu, Joey Liu, Yan Cheng, Feng Liu, Willa A. Hsueh, Tuo Deng   +23 more
wiley   +1 more source

Strategic nanoparticle placement for remote enhancement of boiling heat transfer performance. [PDF]

iScience
Cao C, Peng C, Wu J, Deng J.
europepmc   +1 more source

Experimental investigation of nucleate pool boiling heat transfer characteristics on modified copper surface via laser-structured microstructures

, 2023
Luvindran Sugumaran, Mohd Nashrul Mohd Zubir, K M S Newaz, Tuan Zaharinie, Suazlan Mt Aznam, Aiman Mohd Halil   +5 more
openalex   +1 more source

ZSL Orchestrates Synaptonemal Complex Assembly as a Central Region Scaffold to Ensure Synapsis Fidelity and Crossover Control in Polyploid Meiosis

Advanced Science, Volume 13, Issue 27, 13 May 2026.
A central molecular adaptor, ZSL, is identified that links transverse filaments ZYP1 to central element SCEP1/2 to drive synaptonemal complex assembly in Brassica napus. Loss of ZSL abolishes synaptonemal complex formation, disrupts meiotic chromosome segregation, and markedly increases crossovers, providing mechanistic insight into meiotic fidelity ...
Miaowei Geng, Shaochen Jia, Fei Cao, Cuiping Liu, Heshuang Zhang, Gang Xu, Jixin Zhuang, Yashi Zhang, Can Liu, Yuhang Zhao, Zilin Guo, Xinjie Yuan, Jiaqing Yang, Lei Chu, Bowei Cai, Hu Zhao, Chao Yang   +16 more
wiley   +1 more source