Results 211 to 220 of about 8,087 (328)

Promoter Hypermethylation‐Induced Silencing of FXYD1 Drives Breast Cancer Metastasis via DDX5‐Mediated Wnt/β‐Catenin Pathway Activation

open access: yesAdvanced Science, Volume 13, Issue 27, 13 May 2026.
This study identifies FXYD1 as an epigenetically silenced tumor suppressor in breast cancer. DNA methylation turns off the gene FXYD1 in breast cancer, and low levels predict worse outcomes. Restoring FXYD1 limits breast cancer cells proliferation and metastasis. In the nucleus, FXYD1 recruits the E3 ligase MAEA to K63‐ubiquitinate DDX5 for proteasomal
Ping Wen   +11 more
wiley   +1 more source

Plasma Proteomics Identifies Thousand‐and‐One–Amino Acid Kinase 3 as a Potential Biomarker of Rheumatoid Arthritis Activity and a Novel Therapeutic Target

open access: yesArthritis &Rheumatology, Volume 78, Issue 5, Page 1045-1061, May 2026.
Objective Bone destruction associated with active rheumatoid arthritis (RA) remains a major therapeutic challenge, with a lack of reliable molecular markers reflecting bone injury. This study aims to identify novel biomarkers linked to bone destruction in active RA through proteomic analysis, providing new strategies for precise monitoring and targeted
Pengfei Xin   +15 more
wiley   +1 more source

Neuroprotective Effects of Carnosine Against Corticosterone‐Induced Depression and Memory Impairment

open access: yesFood Science &Nutrition, Volume 14, Issue 5, May 2026.
This main findings of the study and illustrates the key workflow. ABSTRACT Corticosterone (Crt) is reported to induce oxidative stress in experimental animals. Carnosine (Crn), a well‐known dipeptide antioxidant synthesized endogenously from β‐alanine and L‐histidine, neutralizes oxidative stress. The current study examines the influences of Crn on Crt‐
Muneezah Elahi   +6 more
wiley   +1 more source

Heat Transfer Performance of Biphilic Surfaces With Diatomite‐Based Composite Coatings in a Closed Thermosyphon System

open access: yesHeat Transfer, Volume 55, Issue 3, Page 1608-1638, May 2026.
ABSTRACT This study investigates the thermal performance of innovative biphilic boiling surfaces designed for CPU cooling applications using a two‐phase closed thermosyphon (TPCT) system. The surfaces were fabricated by applying composite coatings—comprising epoxy resin and diatomite particles functionalized with APTES and PFOTS silanes— onto Al1050 ...
José Pereira   +3 more
wiley   +1 more source

Accelerating Multiparametric Quantitative MRI Using Self‐Supervised Scan‐Specific Implicit Neural Representation With Model Reinforcement

open access: yesMagnetic Resonance in Medicine, Volume 95, Issue 5, Page 2963-2979, May 2026.
ABSTRACT Purpose To develop a self‐supervised scan‐specific deep learning framework for reconstructing accelerated multiparametric quantitative MRI (qMRI). Methods We propose REFINE‐MORE (REference‐Free Implicit NEural representation with MOdel REinforcement), combining an implicit neural representation (INR) architecture with a model reinforcement ...
Ruimin Feng   +3 more
wiley   +1 more source

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