Results 231 to 240 of about 8,087 (328)

Dualsteric Agonist for M2 Muscarinic Receptor Causes Oxidative Stress and Mitochondrial Alteration in Human Glioblastoma Cancer Stem Cells

open access: yesJournal of Neurochemistry, Volume 170, Issue 5, May 2026.
Dualsteric agonist N8‐iper shows cytotoxic effects on glioblastoma cancer stem cells, but not on human normal astrocytes. Lipid accumulation appears as a consequence of cytotoxic stress; in fact, they are not present in healthy astrocytes. ABSTRACT Glioblastoma (GB) is the most malignant form of human brain tumor, characterized by heterogeneous cell ...
Claudia Guerriero   +11 more
wiley   +1 more source

Unveiling the fundamentals of flow boiling heat transfer enhancement on structured surfaces. [PDF]

open access: yesSci Adv
Inanlu MJ   +12 more
europepmc   +1 more source

The Rice Stripe Virus p2 Interacts With Lsm1 and Disrupts the Lsm1‐Lsm4 Complex to Facilitate the Viral infection

open access: yesMolecular Plant Pathology, Volume 27, Issue 5, May 2026.
RSV p2 binds Lsm1, disrupting Lsm1‐Lsm4 association and impairing decapping‐dependent mRNA decay in P‐bodies, leading to the accumulation of unstable mRNAs and enhanced RSV infection. ABSTRACT Processing bodies (P‐bodies) play central roles in RNA metabolism and in the regulation of viral infection.
Anqi Hu   +12 more
wiley   +1 more source

Transcription Profiling of Potato Leaves in Response to Heat Stress at Single‐Cell Resolution

open access: yesPlant Biotechnology Journal, Volume 24, Issue 5, Page 2970-2987, May 2026.
ABSTRACT Potato (Solanum tuberosum L.) is a globally important food crop with considerable nutritional and economic value. Heat stress significantly inhibits potato plant growth and tuber development, constraining the sustainable development of the potato industry. Currently, studies on the cellular‐level mechanisms underlying heat adaptation in potato
Shiqi Wen   +8 more
wiley   +1 more source

Stress Granule‐Associated ZmCTU2 Confers Thermotolerance in Maize via Coordinated Regulation of Proteostasis and ROS Homeostasis

open access: yesPlant Biotechnology Journal, Volume 24, Issue 5, Page 3371-3390, May 2026.
ABSTRACT The escalating global temperatures and intensifying heat stress events pose significant threats to maize productivity worldwide. Uncovering key thermotolerance genes and their functional mechanisms is thus critical for developing climate‐resilient crops.
Yufang Xu   +8 more
wiley   +1 more source

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