Results 31 to 40 of about 622 (258)

Strawberry Notch 1 Acts as a Transcriptional Regulator Driving Oncogenic Programs in Liver Carcinogenesis

Advanced Science, EarlyView.
This study reports that SBNO1 protein is upregulated in several cancer entities. SBNO1 protein interacts with the basal transcription factor TFIID via TAF4, enabling its recruitment to transcription start sites and the modulation of target gene expression.
Sarah Fritzsche, Raisatun Nisa Sugiyanto, Kira Gür, Alina Krumme, Maxime Le Marois, Angelika Fraas, Aslihan Inal, Mario Huerta, Vanessa Henriques, Eva Eiteneuer, Thomas Albrecht, Alphonse Charbel, Michael T. Dill, Carsten Sticht, Carolina De La Torre, Stefan Pusch, Arianeb Mehrabi, Kai Breuhahn, Junfang Ji, Peter Schirmacher, Benjamin Goeppert, Stephanie Roessler   +21 more
wiley   +1 more source

Numerical simulation of single bubble growth and heat transfer considering multi-parameter influence during nucleate pool boiling of water

AIP Advances, 2021
Nucleate boiling is an essential heat exchange method in industry. Due to the complicated mechanisms of the boiling process, prediction of its heat transfer performance has always been challenging. Studying the growth and heat transfer characteristics of
Jingwen Li, Zhen Yang, Yuanyuan Duan
doaj   +1 more source

Enhancement of evaporation rate in subcooled nucleate pool boiling with suspended hydrophilic particles

International Journal of Thermofluids, 2023
In this paper, evaporation rate of nanofluids in subatmospheric pressure with different hydrophilic particles has been experimentally investigated, and compared with deionized water evaporation rate.
Aliasghar Amirzadeh, Mehdi Sohrabi, N.M. Nouri   +2 more
doaj   +1 more source

Ovarian Matrisome Dynamics and αvβ3‐Mediated Regulation in Early Follicular Development

Advanced Science, EarlyView.
The matrisome undergoes dynamic remodeling during early follicular development. Integrin αvβ3 mediates matrisome signals, regulating primordial follicle activation/atresia and secondary follicle growth via Hippo/mTOR pathways, with conserved roles in human ovaries, offering therapeutic targets for ovarian disorders.
Tong Wu, Yanzhi Feng, Qingqing Zhu, Ting Jiang, Yueyue Gao, Kebing Nie, Xianan Tang, Ying Chen, Dianxing Hu, Xudan Yang, Shixuan Wang, Meng Wu, Jinjin Zhang   +12 more
wiley   +1 more source

Experimental study of bubble behaviors and CHF on printed circuit board (PCB) in saturated pool water at various inclination angles

Nuclear Engineering and Technology, 2018
Experiments were performed to investigate bubble behaviors and pool boiling Critical Heat Flux (CHF) on a thin flat rectangular copper heater fabricated on Printed Circuit Board (PCB), at various inclination angles. The surface inclination angles were 0°,
Elvira F. Tanjung, Bernard O. Alunda, Yong Joong Lee, Daeseong Jo   +3 more
doaj   +1 more source

Acoustic Emission in Subcooled Nucleate Pool Boiling [PDF]

Journal of Nuclear Science and Technology, 1977
Intensity and power spectral density of acoustic emission in subcooled nucleate pool boiling of water from boiling inception to the heater burnout was investigated experimentally. Platinum and Ni-Cr wires with dia. 1.0 mm or smaller were used as the heater.
Hideaki NISHIHARA, Yasunori BESSHO
openaire   +1 more source

Stochastic Nanoscale Biophysical Cues as a Basis for the Induction of Glioblastoma‐Like Transcriptional Programs in Astrocytes

Advanced Science, EarlyView.
Stochastic nanoscale physical cues induce glioblastoma (GBM)‐associated transcriptional traits in naïve astrocytes leading to spontaneous formation of spheroids. Cells within spheroids express activated‐MMP2 and a differential gene expression pattern involving P53 and NOTCH3, providing evidence for a role for changes in brain topography, as observed in
Laurent Starck, Tobias Butelmann, Sabrina Hogan, Melika Sarem, Bernd Heimrich, Ritwick Sawarkar, Marie‐Françoise Ritz, Gregor Hutter, V. Prasad Shastri   +8 more
wiley   +1 more source

A Novel Function of Nonadecanoic Acid in Regulating Glucose Homeostasis

Advanced Science, EarlyView.
This study identifies the odd‐chain fatty acid C19:0 as an endogenous ligand of GPR120 that promotes glucose homeostasis via Gαq signaling. In obesity, elevated palmitic acid suppresses endogenous C19:0 production through a miRNA–PPARα–HACL1 pathway, offering a promising direction for understanding the role of OCFAs in human health.
Yanting Hou, Yinghua Ma, Qin Liu, Dingling Ma, Yuxin Tong, Lili Xu, Xiaolong Chu, Jingzhou Wang, Maodi Liang, Mengyuan Zhao, Huizi Zhang, Yurui Su, Jianxin Xie, Cuizhe Wang, Jun Zhang   +14 more
wiley   +1 more source

Experiment Study of Pool Nucleate Boiling Heat Transfer of Aqueous LiBr Solution at Normal Atmospheric Pressure

Zhileng xuebao, 2013
Boiling regeneration of liquid desiccant solution, which can reduce desiccant air-conditioning’s dependence on the state of regenerator air, is different from spraying-type regeneration.
Xu Huibin, Song Xinnan, Ge Fenghua, Hu Zicheng, Gu Feng   +4 more
doaj  

Testicular mRNA‐LNP Delivery: A Novel Therapy for Genetic Spermatogenic Disorders

Advanced Science, EarlyView.
In the current study, we developed a novel therapy for genetic spermatogenic disorders. It was revealed that in vivo delivery of mRNA LNP3 could restore spermatogenesis in Msh5D486Y/D486Y and Maps KO mouse models with meiotic arrest. Notably, the offspring without genomic integration was born using ICSI derived from the rescue of Msh5D486Y/D486Y mouse ...
Chenwang Zhang, Nan Liang, Wenbo Li, Shuai Xu, Peng Li, Wanze Ni, Na Li, Sha Han, Ningjing Ou, Haowei Bai, Yuxiang Zhang, Furong Bai, Yifan Sun, Dewei Qian, Xinjie Bu, Erlei Zhi, Ruhui Tian, Yuhua Huang, Jingpeng Zhao, Fujun Zhao, Hao Chen, Zheng Li, Chencheng Yao   +22 more
wiley   +1 more source