Results 101 to 110 of about 2,228,594 (330)

From quark and nucleon correlations to discrete symmetry and clustering in nuclei

open access: yes, 2017
Starting with a quark model of nucleon structure in which the valence quarks are strongly correlated within a nucleon, the light nuclei are constructed by assuming similar correlations of the quarks of neighboring nucleons.
Musulmanbekov, Genis
core   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

Semi-realistic nucleon-nucleon interactions with improved neutron-matter properties

open access: yes, 2013
New parameter-sets of the semi-realistic nucleon-nucleon interaction are developed, by modifying the M3Y interaction but maintaining the tensor channels and the longest-range central channels.
H. Nakada, H. Nakada, R. B. Firestone
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

A comprehensive investigation of alpha decay fine structure in odd-odd and odd-even nuclei [PDF]

open access: yesЯдерна фізика та енергетика
We conducted a comprehensive investigation of the alpha decay fine structure in odd-even and odd-odd nuclei with atomic numbers between 95 and 101. Utilizing the cubic plus Yukawa plus exponential model, we considered the combined effects of Coulomb ...
R. Nithya Agnes   +3 more
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

The Seed Nuclear Proteome

open access: yesFrontiers in Plant Science, 2012
Understanding the regulatory networks coordinating seed development will help to manipulate seed traits, such as protein content and seed weight, in order to increase yield and seed nutritional value of important food crops, such as legumes.
Ombretta eRepetto   +4 more
doaj   +1 more source

Separation and Surface Nuclei Effects in a Cavitation Susceptibility Meter [PDF]

open access: yes, 1991
This work is concerned with the effects of flow separation and surface nuclei on the operation of a fixed geometry Cavitation Susceptibility Meter (CSM) with laminar flow. Cavitation is induced under controlled conditions at the throat of a glass venturi
Acosta, A. J., d'Agostino, L.
core  

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

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