Results 81 to 90 of about 1,599,458 (351)

A deep learning algorithm for one-step contour aware nuclei segmentation of histopathology images [PDF]

open access: yesMedical and Biological Engineering and Computing, 2018
This paper addresses the task of nuclei segmentation in high-resolution histopathology images. We propose an automatic end-to-end deep neural network algorithm for segmentation of individual nuclei.
Yuxin Cui   +4 more
semanticscholar   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Polarized structure functions of nucleons and nuclei

open access: yes, 2008
We determine the quark distributions and structure functions for both unpolarized and polarized DIS of leptons on nucleons and nuclei. The scalar and vector mean fields in the nucleus modify the motion of the quarks inside the nucleons.
Yazaki, K.   +4 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

A simple filtration technique for obtaining purified human chromosomes in suspension

open access: yesBioTechniques, 2014
Here we present a simple method for cleaning polyamine human mitotic chromosomes in solution. This was achieved by filtering intact (unburst) nuclei along with both large and small cytoplasmic debris through a series of different pore sized filters. Pure
Mohammed Yusuf   +3 more
doaj   +1 more source

Exotic nuclei [PDF]

open access: yesВестник Российской академии наук, 2019
One of the most interesting and intensively examined research directions in nuclear physics, i.e., the production and investigation of exotic nuclei in the vicinity of drip-lines is investigated. An historical overview of the development of research area is provided.
openaire   +1 more source

Fast, fully automated segmentation of thalamic nuclei from structural MRI

open access: yesNeuroImage, 2019
The thalamus and its nuclei are largely indistinguishable on standard T1 or T2 weighted MRI. While diffusion tensor imaging based methods have been proposed to segment the thalamic nuclei based on the angular orientation of the principal diffusion tensor,
Jason Su   +6 more
semanticscholar   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Revisiting the Unified Model of Active Galactic Nuclei [PDF]

open access: yes, 2015
This review describes recent developments related to the unified model of active galactic nuclei (AGNs). It focuses on new ideas about the origin and properties of the central obscurer (torus) and the connection to its surroundings.
H. Netzer
semanticscholar   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

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