Results 141 to 150 of about 788,142 (267)

siRNA Delivery via Cross‐Linked Gelatin Microparticles Enables Targeted Modulation of Osteogenic‐Vascular Cross‐Talk: An Advanced Human 3D in Vitro Test System for Therapeutic siRNA

Advanced Healthcare Materials, EarlyView.
Osteogenic‐angiogenic cross‐talk is a vital prerequisite for vascularized bone regeneration. In this study, we investigated the effects of siRNA‐mediated silencing of two inhibitory proteins, Chordin and WWP‐1, via CaP‐NP‐loaded gelatin microparticles in osteogenically differentiated microtissues.
Franziska Mitrach, Jonas Kubat, Stefan Simm, Alexandra H. Springwald, Burak Demir, Anton Liebezeit, Michael C. Hacker, Michaela Schulz‐Siegmund   +7 more
wiley   +1 more source

Optimization of Brain Tissue Preservation for Nucleic Acid Stability. [PDF]

J Histochem Cytochem
Novelli M, Smith CC, Maskey D, Stevens J, Gimeno M, Horadagoda N, Sutherland GT.   +6 more
europepmc   +1 more source

INFLUENCE OF PHYSICAL STATE OF CHROMATIN ON NUCLEIC ACID AND PROTEIN SYNTHESIS AND ON RADIATION SENSITIVITY OF CELL DIVISION. Comprehensive Report, June 1, 1966--August 31, 1969.

, 1969
Mary Esther Gaulden
openalex   +2 more sources

HullRad: Fast Calculations of Folded and Disordered Protein and Nucleic Acid Hydrodynamic Properties [PDF]

, 2018
Patrick J. Fleming, Karen G. Fleming
openalex   +1 more source

Engineered ETS1‐Nanoconjugate Restores Immune Homeostasis through Dual Immune‐Vascular Modulation in Relapsing and Progressive Multiple Sclerosis

Advanced Healthcare Materials, EarlyView.
The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang, Si‐Bo Yang, Yan Luo, Xiao‐Di Sun, Bo‐Hao Chang, Da‐Qiang Zhou, Jun‐Jie Jiang, Ya‐Nan Li, Jie‐Hong Wu, Hui‐Juan Jin, Hang Yang, Hang Hu, Yi‐Fan Zhou, Bo Hu   +13 more
wiley   +1 more source

Regulation of R-loops by nucleic acid and protein modifications. [PDF]

Essays Biochem
Zhang Y, Zheng X, Ye S, Ma Y, Jin J.
europepmc   +1 more source

2P119 Nitrogen-15 NMR spectroscopic studies of Ag(I)-mediated C-C base-pairs(05A. Nucleic acid: Structure & Property,Poster,The 52nd Annual Meeting of the Biophysical Society of Japan(BSJ2014))

, 2014
Takenori Dairaku, Kyoko Furuita, Itaru Okamoto, Shuji Oda, Daichi Yamanaka, Yoshinori Kondo, Akira Ono, Chojiro Kojima, Vladimı́r Sychrovský, Yoshiyuki Tanaka   +9 more
openalex   +2 more sources

Intrinsically Disordered Protein‐Inspired Nanovector‐Based Coacervates for the Direct Cytosolic Transport of Biomacromolecules

Advanced Materials, EarlyView.
Intrinsically disordered protein‐inspired nanovectors (IDP‐NVs) form stable nanocoacervates (NCs) with diverse biomacromolecules. In situ conformational changes confer stability and adaptability to NCs under dynamically changing physiological conditions.
Soyeong Jin, Hyemin Park, Seuk‐Min Ryu, Dagyeong Guk, Jaeeun Lee, Seongeon Jin, Changjoon Keum, Jinyoung Park, Myoung‐Hwan Park, Chaekyu Kim, Hojun Kim, Jaegeun Noh, Kwan Hyi Lee, Ja‐Hyoung Ryu, Youngdo Jeong   +14 more
wiley   +1 more source

New targets and procedures for validating the valence geometry of nucleic acid structures. [PDF]

Nucleic Acids Res
Černý J, Nicholls RA, Brzezinski D, Berman HM, Gilski M, Joosten RP, Kowiel M, Lawson CL, Moriarty NW, Richardson JS, Schneider B, Vonrhein C, Williams CJ, Jaskólski M, Egli M.   +14 more
europepmc   +1 more source

1P119 How transcription factor can bypass obstacles? : Molecular simulation approaches(04. Nucleic acid binding proteins,Poster,The 52nd Annual Meeting of the Biophysical Society of Japan(BSJ2014))

, 2014
Mami Saito, Tsuyoshi Terakawa, Shoji Takada   +2 more
openalex   +2 more sources