Results 141 to 150 of about 183,908 (336)

Development of a rapid and highly sensitive nucleic acid-based diagnostic test for schistosomes, leveraging on identical multi-repeat sequences

Frontiers in Parasitology
IntroductionSchistosomiasis (Bilharzia), a neglected tropical disease caused by Schistosoma parasites, afflicts over 240 million people globally, disproportionately impacting Sub-Saharan Africa.
Ombeni Ally, Ombeni Ally, Bernard N. Kanoi, Shwetha Kamath, Clement Shiluli, Eric M. Ndombi, Eric M. Ndombi, Maurice Odiere, Gerald Misinzo, Steven Ger Nyanjom, Chunduri Kiran Kumar, Lucy Ochola, Srinivasa Raju Lolabattu, Jesse Gitaka   +13 more
doaj   +1 more source

Unlocking the Potential of MXene‐Based Electrochemical Biosensors: A Review of Biofunctionalization Strategies and Biosensing Principles

Advanced Materials Technologies, EarlyView.
ABSTRACT Electrochemical biosensors enable the accurate and timely detection of clinical biomarkers, improving healthcare and precision medicine. MXene nanosheets, a class of 2D transition metal carbides, nitrides, and carbonitrides, are promising materials for developing next‐generation electrochemical biosensors due to their unique physicochemical ...
Muhsin Ali, Sharat Chandra Barman, Isobel Steer, Aya H. Alshareef, Dana Alsulaiman   +4 more
wiley   +1 more source

The role of cartridge-based nucleic acid amplification test (CBNAAT) in early diagnosis of extra pulmonary tuberculosis – a case report

Journal of Oral Medicine and Oral Surgery
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. It primarily affects the lungs, leading to Hemoptysis, which is the most frequent manifestation.
Gowda Venkatesha Ramachandra Reddy, Rajaram Mohan Karthik, Ganesh Vinitha, Mathew Fenn Saramma, Rathanswamy Thiruneervannan Reethika Rathan, Gokulraj Sabitha   +5 more
doaj   +1 more source

Nucleic Acid Amplification Testing for Neisseria gonorrhoeae [PDF]

The Journal of Molecular Diagnostics, 2006
David M. Whiley, John W. Tapsall, Theo P. Sloots   +2 more
openaire   +1 more source

Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization

Advanced Science, EarlyView.
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin, Mengjie Zhang, Wenying Liu, Wenlong Shen, Debao Li, Hongming Miao, Fang Deng, Gang Zhang, Yi Tian, Yi Zhang, Zhihu Zhao, Bing Ni   +11 more
wiley   +1 more source

Detection of Parasites in the Field: The Ever-Innovating CRISPR/Cas12a

Biosensors
The rapid and accurate identification of parasites is crucial for prompt therapeutic intervention in parasitosis and effective epidemiological surveillance.
Xin Li, Zhisheng Dang, Wenqiang Tang, Haoji Zhang, Jianwei Shao, Rui Jiang, Xu Zhang, Fuqiang Huang   +7 more
doaj   +1 more source

A gamepad-like nucleic acid testing device for rapid detection of SARS-CoV-2 via visible nested RPA amplification [PDF]

, 2023
Jingwei Bai, Ce Liu, Baobao Lin, Guohua Yuan, Zhi Geng, Zhe Zhao, Jiacheng Wang, Jing-Yu Shao, Zhenqi Wang, Yang Xu, Xujuan Yang, Chang Liu, Yingmei Feng, Xin Fan, Jing Wang, Lili Ren, Yan Xiao, Conghui Wang, Guang Huan Shen, Yi Yang, Chao Zhao, Yinqing Li, Peng Liu   +22 more
openalex   +1 more source

Single cell transcriptome analysis using next generation sequencing. [PDF]

, 2010
The heterogeneity of tissues, especially in cancer research, is a central issue in transcriptome analysis. In recent years, research has primarily focused on the development of methods for single cell analysis. Single cell analysis aims at gaining (novel)
Blattner, M.
core   +1 more source

CypD Dependent mPTP Opening Is Crucial for Oxidized Mitochondrial DNA Release in Ferroptosis

Advanced Science, EarlyView.
Ferroptosis is driven by mitochondrial permeability transition pore (mPTP) opening, which induces mitochondrial swelling and releases oxidized mitochondrial DNA. The released mtDNA activates cGAS–STING signaling, promotes ferritinophagy, and amplifies ferroptotic cell death. Disruption of mtDNA repair sensitizes tumors to ferroptosis in vivo, revealing
Hong Zhou, Wan Fu, Shizuo Liu, Zili Zhang, Hanyan Luo, Qing Zhong   +5 more
wiley   +1 more source

A modular paper-and-plastic device for tuberculosis nucleic acid amplification testing in limited-resource settings [PDF]

, 2019
Navjot Kaur, Joy S. Michael, Bhushan J. Toley   +2 more
openalex   +1 more source