An outlook on coronavirus disease 2019 detection methods
Diagnostic testing plays a fundamental role in the mitigation and containment of coronavirus disease 2019 (COVID-19), as it enables immediate quarantine of those who are infected and contagious and is essential for the epidemiological characterization of
Zahra Hassani Nejad +2 more
doaj +1 more source
Value and Challenges: Nucleic Acid Amplification Tests for SARS-CoV-2 in Hospitalized COVID-19 Patients. [PDF]
Meng Y +6 more
europepmc +3 more sources
Digital nucleic acid amplification tests enable absolute quantification of nucleic acids, but the generation of uniform compartments and reading of the fluorescence requires specialized instruments that are costly, limiting their widespread applications.
Linzhe Chen +4 more
doaj +1 more source
A New ELISA Using the ANANAS Technology Showing High Sensitivity to diagnose the Bovine Rhinotracheitis from Individual Sera to Pooled Milk [PDF]
Diagnostic tests for veterinary surveillance programs should be efficient, easy to use and, possibly, economical. In this context, classic Enzyme linked ImmunoSorbent Assay (ELISA) remains the most common analytical platform employed for serological ...
Brocchi, Emiliana +7 more
core +12 more sources
A portable system for economical nucleic acid amplification testing
Introduction: Regular and rapid large-scale screening for pathogens is crucial for controlling pandemics like Coronavirus Disease 2019 (COVID-19). In this study, we present the development of a digital point-of-care testing (POCT) system utilizing microfluidic paper-based analytical devices (μPADs) for the detection of SARS-CoV-2 gene fragments.
Hui Dong +10 more
openaire +3 more sources
A fully integrated paperfluidic molecular diagnostic chip for the extraction, amplification, and detection of nucleic acids from clinical samples [PDF]
Paper diagnostics have successfully been employed to detect the presence of antigens or small molecules in clinical samples through immunoassays; however, the detection of many disease targets relies on the much higher sensitivity and specificity ...
Dewar, Rajan +4 more
core +2 more sources
Ratiometric Fluorescence Coding for Multiplex Nucleic Acid Amplification Testing [PDF]
Although nucleic acid amplification testing (NAAT) has become the cornerstone for molecular diagnosis of diseases, expanding the multiplexed detection capacity of NAAT remains an important objective. To this end, encoding each nucleic acid target with a specific fluorescently labeled probe has been the most mature approach for multiplexed detection ...
Ye Zhang +3 more
openaire +2 more sources
APPLICATION OF NUCLEIC ACID AMPLIFICATION TESTS IN MANAGING COVID-19 PANDEMIC
Background. COVID-19 pandemic highlighted an importance of sensitive and specific tests that would be cost-efficient, fast and scalable. There are more than 200 COVID-19 detection tests available worldwide, with every country developing own assays ...
Serhiy Souchelnytskyi +1 more
doaj +1 more source
Extraintestinal strongyloidiasis is rare in patients without immunosuppression. We describe the first case of chylous ascites as a result of strongyloidiasis.
Lukas Antonitsch +2 more
doaj +1 more source
Nanoparticle labels for pathogen detection through nucleic acid amplification tests [PDF]
YesMagnetic nanoparticles and surface-enhanced Raman scattering (SERS) active nanoparticles were coated with short chain DNA tags. These were then used to identify a target bacterial DNA sequence.
Chen, Y-C. +3 more
core +1 more source

