Woven Electroanalytical Biosensor for Nucleic Acid Amplification Tests
AbstractFiber‐based biosensors enable a new approach in analytical diagnostic devices. The majority of textile‐based biosensors, however, rely on colorimetric detection. Here a woven biosensor that integrates microfluidics structures in combination with an electroanalytical readout based on a thiol‐self‐assembled monolayer (SAM) for Nucleic Acid ...
Khaliliazar, Shirin +5 more
openaire +4 more sources
Nucleic acid amplification tests for diagnosis of smear-negative TB in a high HIV-prevalence setting: a prospective cohort study. [PDF]
Nucleic acid amplification tests are sensitive for identifying Mycobacterium tuberculosis in populations with positive sputum smears for acid-fast bacilli, but less sensitive in sputum-smear-negative populations.
J Lucian Davis +9 more
doaj +1 more source
Non-instrumented nucleic acid amplification tests (NINAAT) are a novel paradigm in portable molecular diagnostics. They offer the high detection accuracy characteristic of nucleic acid amplification tests (NAAT) in a self-contained device, without the ...
Tamás Pardy, Toomas Rang, Indrek Tulp
doaj +1 more source
Development of rapid, automated diagnostics for infectious disease: advances and challenges [PDF]
The last 2 years has seen an exponential rise in the amount of research funding made available for the development of rapid diagnostic devices for infectious agents of medical importance. This review reports on several such projects.
Ince, J, McNally, A
core +1 more source
Standardization of nucleic acid amplification tests in diagnostic molecular microbiology
Nucleic acid detection by amplification (NAT) assays began to be used in diagnostic microbiology about twenty years ago. Since then, the progress of molecular methods has been continuous and rapid, aimed to obtain more and more sensitive and specific ...
Alberta Azzi +6 more
doaj +1 more source
Progress on the development of rapid diagnostic tests for foodborne neglected zoonotic helminthiases : a systematic review [PDF]
Background: Foodborne Neglected Zoonotic Helminths (FNZH) are parasites of both economic and public health importance. They include Taenia solium, Echinococcus granulosus sensu lato, Echinococcus multilocularis and Foodborne trematodes (FBT).
Chabala, Chishala +9 more
core +1 more source
Designs and applications of microfluidics-based devices for molecular diagnostics (Nucleic Acid Amplification Tests, NAATs) in infectious disease testing are reviewed, with emphasis on minimally instrumented, point-of-care (POC) tests for resource ...
Michael G. Mauk +3 more
doaj +1 more source
Pooled nucleic acid amplification tests for severe acute respiratory syndrome coronavirus 2 could increase availability of testing at decreased cost.
Hannah Wang +10 more
doaj +1 more source
A paperfluidic platform to detect Neisseria gonorrhoeae in clinical samples [PDF]
Globally, the microbe Neisseria gonorrhoeae (NG) causes 106 million newly documented sexually transmitted infections each year. Once appropriately diagnosed, NG infections can be readily treated with antibiotics, but high-risk patients often do not ...
Cabodi, Mario +7 more
core +1 more source
Differential DNA accessibility to polymerase enables 30-minute phenotypic β-lactam antibiotic susceptibility testing of carbapenem-resistant Enterobacteriaceae [PDF]
The rise in carbapenem-resistant Enterobacteriaceae (CRE) infections has created a global health emergency, underlining the critical need to develop faster diagnostics to treat swiftly and correctly.
Garner, Omai B. +5 more
core +1 more source

