Ultrafast Microfluidic PCR Thermocycler for Nucleic Acid Amplification
Micromachines, 2023 The polymerase chain reaction (PCR) is essential in nucleic acid amplification tests and is widely used in many applications such as infectious disease detection, tumor screening, and food safety testing; however, most PCR devices have inefficient ...
Yi-Quan An +10 more
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A cost effective real-time PCR for the detection of adenovirus from viral swabs [PDF]
, 2013 Compared to traditional testing strategies, nucleic acid amplification tests such as real-time PCR offer many advantages for the detection of human adenoviruses. However, commercial assays are expensive and cost prohibitive for many clinical laboratories.
Jason J LeBlanc +7 more
core +1 more source
Evaluation of Xpert® MTB/RIF and ustar easyNAT™ TB IAD for diagnosis of tuberculous lymphadenitis of children in Tanzania : a prospective descriptive study [PDF]
, 2016 Fine needle aspiration biopsy has become a standard approach for diagnosis of peripheral tuberculous lymphadenitis. The aim of this study was to compare the performance of Xpert MTB/RIF and Ustar EasyNAT TB IAD nucleic acid amplification assays, against ...
AT Cruz +39 more
core +3 more sources
Tuberculosis diagnostics and biomarkers: needs, challenges, recent advances, and opportunities [PDF]
, 2012 Tuberculosis is unique among the major infectious diseases in that it lacks accurate rapid point-of-care diagnostic tests. Failure to control the spread of tuberculosis is largely due to our inability to detect and treat all infectious cases of pulmonary
Alexandre Harari +118 more
core +2 more sources
Development of a SimpleProbe real-Time PCR Assay for rapid detection and identification of the US novel urethrotropic clade of Neisseria meningitidis ST-11 (US_NmUC) [PDF]
, 2020 Urethritis, or inflammation of the urethra, is one of the most common reasons men seek clinical care. Sexually transmitted pathogens including Neisseria gonorrhoeae are responsible for over half of the symptomatic urethritis cases in U.S. men.
Ermel, Aaron +4 more
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Semiquantitative Nucleic Acid Test with Simultaneous Isotachophoretic Extraction and Amplification [PDF]
Analytical Chemistry, 2018 Nucleic acid amplification tests (NAATs) provide high diagnostic accuracy for infectious diseases and quantitative results for monitoring viral infections. The majority of NAATs require complex equipment, cold chain dependent reagents, and skilled technicians to perform the tests.
Andrew T. Bender +5 more
openaire +2 more sources
Clinical application of high throughput molecular screening techniques for pharmacogenomics. [PDF]
, 2011 Genetic analysis is one of the fastest-growing areas of clinical diagnostics. Fortunately, as our knowledge of clinically relevant genetic variants rapidly expands, so does our ability to detect these variants in patient samples.
Schrijver, Iris, Wiita, Arun P
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The Laboratory Diagnosis of Neisseria gonorrhoeae
Canadian Journal of Infectious Diseases and Medical Microbiology, 2005 The present article describes the laboratory diagnosis of Neisseria gonorrhoeae by culturing of the organism from different types of clinical specimens followed by confirmatory tests.
Lai-King Ng, Irene E Martin
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Amplification efficiency and thermal stability of qPCR instrumentation: Current landscape and future perspectives [PDF]
, 2015 This is a final draft version of the publication following acceptance by the journal.Quantitative polymerase chain reaction (qPCR) is a method of amplifying and detecting small samples of genetic material in real time and is in routine use across many ...
Karteris, E, Rogers-Broadway, KR
core +1 more source
SensorsNucleic acid tests are key tools for the detection and diagnosis of many diseases. In many cases, the amplification of the nucleic acids is required to reach a detectable level. To make nucleic acid amplification tests more accessible to a point-of-care (
Bethany J. Fike +2 more
doaj +1 more source