Results 131 to 140 of about 364,067 (350)
Diagnosis of active tuberculosis disease: From microscopy to molecular techniques
Journal of Clinical Tuberculosis and Other Mycobacterial Diseases, 2016 Methods used for the laboratory diagnosis of tuberculosis are continually evolving in order to achieve more rapid, less expensive, and accurate results.
Adam J. Caulfield, Nancy L. Wengenack
doaj
A physicist's view of DNA [PDF]
De Physicus, 24e, 3, 59-61 (2013), 2013 Nucleic acids, like DNA and RNA, are molecules that are present in any life form. Their most notable function is to encode biological information. Why then would a physicist be interested in these molecules? As we will see, DNA is an interesting molecular tool for physicists to test and explore physical laws and theories, like the ergodic theorem, the ...
arxiv
Advanced Science, EarlyView.This study discovers that SIRT1, a hub gene involved in glucolipid metabolic conversion in colorectal carcinoma (CRC), stimulates CX3CL1 secretion in CRC cells by activating FOXO1. The CX3CL1‐CX3CR1 signaling promotes the differentiation of TCF7+ regulatory T cells (Tregs) into an enhanced immunosuppressive TNFRSF9+ Treg phenotype.
Ruiyang Zi +18 more
wiley +1 more source
Mechanism of thermal renaturation and hybridization of nucleic acids: Kramers process and universality in Watson-Crick base pairing [PDF]
arXiv, 2008 Renaturation and hybridization reactions lead to the pairing of complementary single-stranded nucleic acids. We present here a theoretical investigation of the mechanism of these reactions in vitro under thermal conditions (dilute solutions of single-stranded chains, in the presence of molar concentrations of monovalent salts and at elevated ...
arxiv
Monoadduct forming photochemical reagents for labeling nucleic acids for hybridization [PDF]
, 1989 James P. Albarella +4 more
openalex +1 more source
FUS Selectively Facilitates circRNAs Packing into Small Extracellular Vesicles within Hypoxia Neuron
Advanced Science, EarlyView.This study aimed to unravel the role of FUS in the loading of functional circRNAs into neuronal sEVs under hypoxic conditions, which involves their aggregations in SGs and specific interaction between the FUS Zf_RanBP domain to regulate circRNA sorting in sEVs.
Jiankun Zang +14 more
wiley +1 more source
Aggregate, Volume 3, Issue 6, December 2022., 2022 The aggregation‐induced emission luminogens (AIEgens) propel the development of drug and gene delivery systems. The lit‐up AIEgens first serve for real‐time monitoring of the delivery processes and evaluation of therapeutic responses of drug/gene. The delicate design of AIEgens to form high‐level structural carrier remarkably enhances the delivery ...
Jie Sun, Xuewen He
wiley +1 more source
The use of heparin as a simple cost-effective means of controlling background in nucleic acid hybridization procedures [PDF]
, 1984 L. Singh, K.W. Jones
openalex +1 more source
Advanced Science, EarlyView.Hepatoblastoma, an aggressive childhood liver tumor, origins from malignant hepatoblast‐like cells. Single‐cell analysis reveals IGF2‐driven pathways promoting malignancy. Targeting these pathways offers promising treatments, with serum IGF2 as a potential diagnostic biomarker.
Miao Ding +12 more
wiley +1 more source