Advanced Science, EarlyView.Enhancer eccANKRD28‐manipulated MM cells have been demonstrated to facilitate drug resistance and promote MM progression by activating the key transcription factor, POU2F2. POU2F2 interacts with sequence‐specific eccANKRD28 as well as RUNX1 and RUNX2 motifs to form the protein complex, which activates the promoter of oncogenes (IRF4, JUNB, IKZF3, et al.
Binzhen Chen +12 more
wiley +1 more source
Advanced Science, EarlyView.Enzymatic introduction of azido‐sialic acid residues to the glycans on exosomes enables a new and efficient approach for exosomal functionalization with various probes, including biotin and fluorophores, by biocompatible click chemistry, thereby facilitating detailed investigations of exosomes, such as their glycan profiles, cellular uptake, etc., and ...
Sayan Kundu +5 more
wiley +1 more source
Electrostatic surface plasmon resonance: Direct electric field-induced hybridization and denaturation in monolayer nucleic acid films and label-free discrimination of base mismatches [PDF]
, 2001 Richard J. Heaton +2 more
openalex +1 more source
Advanced Science, EarlyView.The splicing factor PTBP3 promotes COX11 exon skipping, allowing gastric cancer organoids to evade cuproptosis. Antisense oligonucleotide drugs targeting PTBP3‐mediated COX11 alternative splicing, in combination with copper ionophores, promote cuproptosis in organoids, thereby providing a therapeutic approach for gastric cancer peritoneal metastasis ...
Yajing Zhou +11 more
wiley +1 more source
The Role of Structural Enthalpy in Spherical Nucleic Acid Hybridization. [PDF]
J Am Chem Soc, 2018 Fong LK +4 more
europepmc +1 more source
Specific Nucleic Acid Detection Using a Nanoparticle Hybridization Assay [PDF]
arXivSimple methods to detect biomolecules including specific nucleic acid sequences have received renewed attention since the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) virus pandemic. Notably, biomolecule detection that uses some form of signal amplification will have some form of amplification-related error, which in the polymerase ...
arxiv
Differentiation of Candida albicans and Candida dubliniensis by Fluorescent In Situ Hybridization with Peptide Nucleic Acid Probes [PDF]
, 2001 Kenneth Oliveira +4 more
openalex +1 more source
Metal–Organic Frameworks: Unlocking New Frontiers in Cardiovascular Diagnosis and Therapy
Advanced Science, EarlyView.Metal–organic frameworks (MOFs), are composed of metal ions and bridging organic ligands, are recognized as an excellent platform for host‐gust chemistry. Its rich structural composition, modifiable sites, and multilevel pore distribution can provide delivery and release of signaling molecules, probes, and therapeutic drugs, which exhibit great medical
Qilu Wu +6 more
wiley +1 more source
The hybridization-stabilization assay: a solution-based isothermal method for rapid screening and determination of sequence preference of ligands that bind to duplexed nucleic acids [PDF]
, 2001 Carlos González
openalex +1 more source