Results 201 to 210 of about 364,067 (350)
Advanced Science, EarlyView.Multiple therapeutic modalities combined in a synergistic way that can modulate different immune axes are demonstrated potentially effective in boosting immunotherapy. A nucleic acid‐locked smart carrier (NASC) performed as an “all‐in‐one” nanoplatform is constructed for efficient eliciting chemo‐ and photothermal‐amplified immunogenic cell death to ...
Jiayang Zhang +6 more
wiley +1 more source
Effect of Locked Nucleic Acid (LNA) modification on Hybridization Kinetics of DNA duplex [PDF]
, 2008 Amit Arora +3 more
openalex +1 more source
Advanced Science, EarlyView.Abstract Liver cancer stem cells (CSCs) account for tumor initiation, heterogeneity and therapy resistance. However, the role of small nucleolar RNAs (snoRNAs) in the regulation of liver CSCs remains largely unclear. Here, this work identifies a conserved H/ACA box snoRNA SNORA74A which is highly expressed in liver CSCs.
Ziheng Zhou +12 more
wiley +1 more source
ISOLATION AND PROPERTIES OF A NUCLEIC ACID HYBRID POLYMERASE [PDF]
Proceedings of the National Academy of Sciences, 1964 Liebe F. Cavalieri, Sylvia Lee-Huang
openaire +3 more sources
Detection of Huanglongbing (Citrus Greening) Disease by Nucleic Acid Spot Hybridization [PDF]
, 2009 Kuraba Gopal +6 more
openalex +1 more source
High‐Throughput Tiling of Essential mRNAs Increases Potency of Antisense Antibiotics
Advanced Science, EarlyView.The systematic tiling of essential genes’ mRNA here presented, proposes a valuable tool for the identification of novel PNA sequences with antibiotic potential. The high‐throughput synthetic set up opens the door to investigating thousands of sequences in an economic way and ultimately identifies potent antisense oligonucleotides while also giving room
Giorgia Danti +3 more
wiley +1 more source
Recent Advances in Enhancing the Sensitivity of Biosensors Based on Field Effect Transistors
Advanced Electronic Materials, EarlyView.This paper discusses the methods to enhancing the detection sensitivity of biosensors in three aspects: overcoming the influence of Debye shielding effects, promoting the binding efficiency of analytes and transistor surface, and improving the structures of device.
Yuying Zhou +8 more
wiley +1 more source
Cancer Communications, Volume 42, Issue 12, Page 1257-1287, December 2022., 2022 Abstract Clustered regularly interspaced short palindromic repeats‐associated protein (CRISPR/Cas9), an adaptive microbial immune system, has been exploited as a robust, accurate, efficient and programmable method for genome targeting and editing. This innovative and revolutionary technique can play a significant role in animal modeling, in vivo genome
Khaled S. Allemailem +6 more
wiley +1 more source
Advanced Electronic Materials, EarlyView.The single‐molecule with a large transistor‐SiMoT is proposed for the detection of the subgenomic RNA of SARS‐CoV‐2, achieving a diagnostic sensitivity of 98.0% and a specificity of 87.8%. The SiMoT technology, currently at TRL‐5, is suitable for point‐of‐care settings and delivers the result to the end user in 30 min.
Eleonora Macchia +12 more
wiley +1 more source