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Chemical etiology of nucleic acid structure [PDF]

open access: bronzePure and Applied Chemistry, 2000
Abstract The synthesis of potentially natural nucleic acid alternatives and comparison of some of their chemical properties with those of RNA and DNA have led to findings that we consider to be relevant in the context of a chemical etiology of nucleic acid structure.
Eschenmoser, A., Krishnamurthy, R.
semanticscholar   +9 more sources

Psoralen Photochemistry and Nucleic Acid Structure

open access: bronzeJournal of Investigative Dermatology, 1981
Many new psoralen derivatives have been synthesized in an effort to enhance their water solubility and their binding to nucleic acids. Availability of the very soluble strongly binding compounds has improved our abilities to follow the optical changes associated with the photochemistry of psoralens with DNA.
John E. Hearst
semanticscholar   +5 more sources

THE CLASSIC: Molecular Structure of Nucleic Acids [PDF]

open access: yesClinical Orthopaedics & Related Research, 1953
WE wish to suggest a structure for the salt of deoxyribose nucleic acid (D.N.A.). This structure has novel features which are of considerable biological interest. A structure for nucleic acid has already been proposed by Pauling and Corey1. They kindly made their manuscript available to us in advance of publication.
James D. Watson, Francis Crick
openaire   +11 more sources

A structure for deoxyribose nucleic acid

open access: bronzeJournal of the American College of Cardiology, 2003
This past April marked the 50th anniversary of publication of the manuscript describing the double helix structure of deoxyribonucleic acid (DNA) by James Watson and Francis Crick [(1)][1]. This was, of course, truly a landmark publication and has been said to have given birth to the field ...
Anthony N. DeMaria
openaire   +3 more sources

Research progress of triplex nucleic acid in food safety detection

open access: yesShipin yu jixie, 2022
This paper reviews the structure and stability of triplex nucleic acid, the progress of triplex nucleic acid-based fluorescence, electrochemical, colorimetric platform in detecting food borne hazards, and discusses the challenges and future development ...
SUN Hai-yan   +3 more
doaj   +1 more source

DNA Variations between Medicago truncatula Symbiotic Mutant Line and Native Variant Using Fluorescence-Based AFLP Marker

open access: yesHighlights in BioScience, 2020
Genetic mutagenesis is a very efficient tool in studying genes function. Because of the great benefits of legumes as human food and animal feed worldwide, we used a model plant Medicago truncatula for identification gene function related to nitrogen ...
Asmaa Hamdy Hassan   +2 more
doaj   +1 more source

Structure of the Nucleic Acids [PDF]

open access: yesNature, 1953
WE have formulated a structure for the nucleic acids which is compatible with the main features of the X-ray diagram and with the general principles of molecular structure, and which accounts satisfactorily for some of the chemical properties of the substances. The structure involves three intertwined helical polynucleotide chains. Each chain, which is
Linus Pauling, Robert B. Corey
openaire   +3 more sources

blkn, a novel Medicago truncatula mutant achieving black nodule phenotype

open access: yesHighlights in BioScience, 2020
blkn is a Medicago truncatula mutant that is achieving null function-black nodule phenotype. blkn is a Tnt1-retrotransposon mutant, Tnt1 is Nicotiana tabacum retro-transposon which is replicated via RNA copy and integrated in plant genome. Interestingly,
Asmaa Hassan   +3 more
doaj   +1 more source

Viral Mimicry as a Design Template for Nucleic Acid Nanocarriers

open access: yesFrontiers in Chemistry, 2021
Therapeutic nucleic acids hold immense potential in combating undruggable, gene-based diseases owing to their high programmability and relative ease of synthesis.
Ina F. de la Fuente   +4 more
doaj   +1 more source

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