Results 131 to 140 of about 651,023 (306)

Tri‐Layered Bioactive Cutaneous Scaffold with Integrated Bioactive Metal Organic Frameworks to Promote Full‐Thickness Infected Diabetic Wound Healing: Multifaceted Therapeutic Strategies

Advanced Healthcare Materials, EarlyView.
The limitations of existing clinical treatments highlight the need for a more comprehensive strategy for addressing infected diabetic wounds. A tri‐layered scaffold is developed to deliver therapeutics loaded in CuBDC and ZIF‐8 MOFs that are tailored to the requirements of deep‐infected diabetic wounds.
Ayse Gunyakti Mujtaba, Ayşe Karakeçili, Berna Topuz, Barış Batur, Okan Onar, Mehmet Eray Elçiğir, Çağdaş Oto, Alireza Hanifehnezhad, Kaan Orhan   +8 more
wiley   +1 more source

Targeting Nucleic Acid Junctions Using Triptycene-Based Molecules [PDF]

, 2015
Targeting nucleic acids in a structure- or sequence-specific manner with small molecules remains a significant challenge in chemical biology. The ability to modulate a particular nucleic acid structure would allow for the specific control of cellular ...
Barros, Stephanie A
core   +1 more source

Advanced Materials for Biological Field‐Effect Transistors (Bio‐FETs) in Precision Healthcare and Biosensing

Advanced Healthcare Materials, EarlyView.
This review explores how advanced materials enhance Bio‐FETs for precision healthcare and biosensing. It covers their working principles, surface functionalization, and ultra‐sensitive detection capabilities. The integration of flexible designs, AI, and IoT for real‐time monitoring is discussed, along with challenges like material reproducibility and ...
Minal Pandey, Manish Bhaiyya, Prakash Rewatkar, Jitendra B. Zalke, Nitin P. Narkhede, Hossam Haick   +5 more
wiley   +1 more source

Synthesis of Diazaxanthilidenes and Applications in Cellular Imaging [PDF]

, 2016
Natural products have been a valuable source of inspiration for organic chemists, both as synthetic challenges and as potential candidates for drug development or other biological applications.
Tran, Mai Ngoc
core   +1 more source

Berberine-inspired ionizable lipid for self-structure stabilization and brain targeting delivery of nucleic acid therapeutics

Nature Communications
Lipid nanoparticles have shown success in targeting major organs such as the liver, spleen, and lungs, but crossing the blood-brain barrier (BBB) remains a major challenge.
Xufei Bian, Qian Guo, Lee-Fong Yau, Ling Yang, Xiaoyou Wang, Shikang Zhao, Shiqiong Wu, Xurong Qin, Zhi-Hong Jiang, Chong Li   +9 more
doaj   +1 more source

Nucleic acid structure and expression of the human AIDS/lymphadenopathy retrovirus [PDF]

, 1985
Mark A. Muesing, Douglas H. Smith, Cirilo D. Cabradilla, Charles V. Benton, Laurence A. Lasky, Daniel J. Capon   +5 more
openalex   +1 more source

Tumor‐Targeted Exosome‐Based Heavy Atom‐Free Nanosensitizers With Long‐Lived Excited States for Safe and Effective Sono‐Photodynamic Therapy of Solid Tumors

Advanced Healthcare Materials, EarlyView.
Engineered exosome‐based heavy atom‐free nanosensitizers are developed for safe and targeted sono‐photodynamic therapy of solid tumors. The IR820‐TPE‐loaded, biotin‐conjugated exosomes (IR820‐TPE@B‐Exo) demonstrate significant promise for NIR fluorescence imaging‐guided sono‐photodynamic cancer therapy.
Van‐Nghia Nguyen, Thuy Giang Nguyen Cao, Hyunsun Jeong, Quan Truong Hoang, Binh T. T. Pham, Jieun Bang, Chang Woo Koh, Ji Hee Kang, Jeong Hyun Lee, Xiaofeng Wu, Won Jong Rhee, Young Tag Ko, K. M. K. Swamy, Sungnam Park, JaeHong Park, Min Suk Shim, Juyoung Yoon   +16 more
wiley   +1 more source

Two distinct nucleic acid binding surfaces of Cdc5 regulate development [PDF]

, 2019
Cell division cycle 5 (Cdc5) is a highly conserved nucleic acid binding protein among eukaryotes and plays critical roles in development. Cdc5 can simultaneously bind to DNA and RNA by its N- terminal DNA-binding domain (DBD), but molecular mechanisms ...
Li, Guorui, Li, Mu, Liu, Junfeng, Peng, You-Liang, Wang, Chao, Yang, Jun, Yu, Bin, Zhao, Wensheng   +7 more
core   +1 more source

β‐1,3 Glucan Microparticles & Nanoparticles: Fabrication Methods & Applications in Immunomodulation & Targeted Drug Delivery

Advanced Healthcare Materials, EarlyView.
Beta‐glucans have gained significant attention as an immunomodulatory biomaterial with cell‐targeting capabilities. This review comprehensively outlines the design and fabrication methods for producing beta‐glucan particles at both the micro and nanoscale and their applications in immune cell targeting, immunomodulation, and drug delivery ...
Nate Dowdall, Todd Hoare
wiley   +1 more source

Nucleic acid–drug interactions: model studies. The crystal structure of salicylic acid–9-Me-adenine, salicyclic acid–2-amino-pyridine and salicylic acid–urea complexes [PDF]

, 1981
Robert W. Gellert, I.-N. Hsu
openalex   +1 more source