Results 11 to 20 of about 737,876 (305)

Structural Probes in Quadruplex Nucleic Acid Structure Determination by NMR [PDF]

open access: yesMolecules, 2012
Traditionally, isotope-labelled DNA and RNA have been fundamental to nucleic acid structural studies by NMR. Four-stranded nucleic acid architectures studies increasingly benefit from a plethora of nucleotide conjugates for resonance assignments, the ...
Mateus Webba da Silva   +1 more
doaj   +2 more sources

Selenium-derivatized Nucleic Acids for Phasing, Crystal Growth, Structure Determination and Beyond [PDF]

open access: yesStructural Dynamics
Nucleic acids play important roles in life processes, such as genetic material, gene regulation, transcription, protein synthesis, signaling, catalysis, and viral infection.
Zhen Huang, Hehua Liu, Jianhua Gan
doaj   +2 more sources

Crystal Engineering of Nucleic Acid Macro-molecules using Selenium Atoms [PDF]

open access: yesStructural Dynamics
Nucleic acids play important roles in life processes, such as genetic material, gene regulation, protein synthesis, signaling, catalysis, and viral infection.
Zhen Huang, Hehua Liu, Jianhua Gan
doaj   +2 more sources

A workflow to define structural classes and classify nucleic acids circular dichroism spectra [PDF]

open access: yesQRB Discovery
Circular dichroism (CD) spectroscopy is a widely utilized technique for studying the structures of chiral molecules, including nucleic acids. It is particularly valued for its ability to quickly probe structural changes in these biomolecules. Despite its
Kevin Mosca   +5 more
doaj   +2 more sources

Impact of Liposomal Spherical Nucleic Acid Structure on Immunotherapeutic Function [PDF]

open access: yesACS Central Science, 2021
Cassandra E. Callmann   +4 more
doaj   +2 more sources

DNA Variations between Medicago truncatula Symbiotic Mutant Line and Native Variant Using Fluorescence-Based AFLP Marker

open access: yesHighlights in BioScience, 2020
Genetic mutagenesis is a very efficient tool in studying genes function. Because of the great benefits of legumes as human food and animal feed worldwide, we used a model plant Medicago truncatula for identification gene function related to nitrogen ...
Asmaa Hamdy Hassan   +2 more
doaj   +1 more source

blkn, a novel Medicago truncatula mutant achieving black nodule phenotype

open access: yesHighlights in BioScience, 2020
blkn is a Medicago truncatula mutant that is achieving null function-black nodule phenotype. blkn is a Tnt1-retrotransposon mutant, Tnt1 is Nicotiana tabacum retro-transposon which is replicated via RNA copy and integrated in plant genome. Interestingly,
Asmaa Hassan   +3 more
doaj   +1 more source

Research progress of triplex nucleic acid in food safety detection

open access: yesShipin yu jixie, 2022
This paper reviews the structure and stability of triplex nucleic acid, the progress of triplex nucleic acid-based fluorescence, electrochemical, colorimetric platform in detecting food borne hazards, and discusses the challenges and future development ...
SUN Hai-yan   +3 more
doaj   +1 more source

Nucleic acid–protein interfaces studied by MAS solid-state NMR spectroscopy

open access: yesJournal of Structural Biology: X, 2022
Solid-state NMR (ssNMR) has become a well-established technique to study large and insoluble protein assemblies. However, its application to nucleic acid–protein complexes has remained scarce, mainly due to the challenges presented by overlapping nucleic
Philipp Innig Aguion   +2 more
doaj   +1 more source

Viral Mimicry as a Design Template for Nucleic Acid Nanocarriers

open access: yesFrontiers in Chemistry, 2021
Therapeutic nucleic acids hold immense potential in combating undruggable, gene-based diseases owing to their high programmability and relative ease of synthesis.
Ina F. de la Fuente   +4 more
doaj   +1 more source

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