Nanotherapy for Neural Retinal Regeneration
Nanotechnology enhances ophthalmic treatments by improving drug delivery and regenerating ocular tissues, combating vision loss from retinal diseases through innovative nano‐systems. This review outlines ocular anatomy, pathology, immune microenvironment, and barriers, detailing nanocarrier characteristics, classification, and preparation methods, and ...
Chuyao Yu+11 more
wiley +1 more source
Oxford handbook of nucleic acid structure. Edited by Stephen Neidle. Pp. xviii + 662. Oxford University Press, 1999. Price US$140.00. ISBN 0-19-850038-6.Nucleic acids: structures, properties and functions. By Victor A. Bloomfield, Donald M. Crothers and Ignacio Tinoco Jr. Pp. xii + 794. Sausalito: University Science Books, 2000. Price US$79.20. ISBN 0-935702-49-0. [PDF]
Michal Sabat
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The first report of structural analysis of a nucleic acid using crystals grown in space. [PDF]
Ando S, Takahashi M, Kondo J.
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DNA Origami‐Cyanine Nanocomplex for Precision Imaging of KRAS‐Mutant Pancreatic Cancer Cells
DNA origami‐cyanine (Do‐Cy) nanocomplexes are synthesized to selectively image KRAS‐mutant pancreatic cancer cells in the highly desmoplastic tumors. This study shows that the Do‐Cy nanocomplexes are preferentially internalized by cancer cells over other stroma cells via KRAS‐dependent macropinocytosis.
Hye‐ran Moon+7 more
wiley +1 more source
This study verifies that circRNA‐mTOR exhibits high expression levels in HCC and has a strong correlation with patient prognosis. Mechanistically, circRNA‐mTOR achieves this effect by facilitating the nuclear translocation of RNA‐binding protein (RBP) PSIP1 through specific binding.
Yongchang Tang+12 more
wiley +1 more source
The Bacterial Histone-like Protein HU Specifically Recognizes Similar Structures in All Nucleic Acids [PDF]
Anna Balandina+2 more
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Aptamer-engaged nanotherapeutics against SARS-CoV-2. [PDF]
Zhang J+4 more
europepmc +1 more source
SIRT3‐Mediated Deacetylation of DRP1K711 Prevents Mitochondrial Dysfunction in Parkinson's Disease
SIRT3‐mediated deacetylation of DRP1 at K711 resists mitochondrial dysfunction and DA neuronal death in PD, uncovering a treatment target. Abstract Dysregulation of mitochondrial dynamics is a key contributor to the pathogenesis of Parkinson's disease (PD).
Ye Xi+11 more
wiley +1 more source