Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
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Optimization of TX-100/SDS-based decellularized vascular material using ultrasound and chemical treatment: evaluation of structure and biosafety. [PDF]
Chen H +6 more
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The research demonstrates a Mesenchymal Stem Cell‐inspired microneedle platform (MSCi@MN) that addresses chronic diabetic wounds by combining MSC‐derived extracellular nanovesicles (NV)–DNA conjugates in microneedle tips with photothermal MXene in the patch layer.
Chan Ho Moon +21 more
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DRESIS 2.0: the comprehensive landscape of drug resistance information. [PDF]
Sun X +14 more
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Peter Leonard +4 more
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A high‐throughput in vivo mRNA LNP screening platform is developed and employed to screen a large library of 122 mRNA LNPs in vivo for delivery to immune, stromal, and parenchymal cells, identifying promising LNP candidates. A novel small particle flow cytometry‐based protein adsorption analysis method is utilized to interrogate protein corona ...
Alex G. Hamilton +17 more
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New targets and procedures for validating the valence geometry of nucleic acid structures. [PDF]
Černý J +14 more
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High‐Concentration Antibody Formulation via Solvent‐Based Dehydration
Amorphous solid antibodies are encapsulated into hydrogel microparticles through a solvent‐based dehydration process. The solvent extracts water from antibody solution droplets, causing the antibody to concentrate, and precipitation of the antibody into amorphous solid is induced.
Talia Zheng +3 more
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Effect of single xeno-nucleic acid replacement on the fluorescence of DNA-encapsulated silver nanoclusters. [PDF]
Yadavalli HC +8 more
europepmc +1 more source
Unwinding of nucleic acids by HCV NS3 helicase is sensitive to the structure of the duplex
A.J. Tackett +7 more
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