Results 211 to 220 of about 651,023 (306)

The structure and physical chemistry of nucleic acids and nucleoproteins.

, 1960
Peacocke Ar
openalex  

The 1.8 å crystal structure of a statically disordered 17 base-pair RNA duplex: principles of RNA crystal packing and its effect on nucleic acid structure

, 1999
Sapan A. Shah, Axel T. Brünger
openalex   +1 more source

Subtle Alterations of the Native Zinc Finger Structures Have Dramatic Effects on the Nucleic Acid Chaperone Activity of Human Immunodeficiency Virus Type 1 Nucleocapsid Protein [PDF]

, 2002
Jianhui Guo, Tiyun Wu, Bradley F. Kane, Donald G. Johnson, Louis E. Henderson, Robert J. Gorelick, Judith G. Levin   +6 more
openalex   +1 more source

The role of water in mediating DNA structures with epigenetic modifications, higher-order conformations and drug-DNA interactions. [PDF]

RSC Chem Biol
Satange R, Hou MH.
europepmc   +1 more source

Caspase‐6/Gasdermin C‐Mediated Tumor Cell Pyroptosis Promotes Colorectal Cancer Progression Through CXCL2‐Dependent Recruitment of Myeloid‐Derived Suppressor Cells

Advanced Science, EarlyView.
Hypoxic and low‐glucose conditions in tumor tissues trigger colorectal tumor cell pyroptosis via sequential activation of the Caspase‐1/Caspase‐6/GSDMC axis. High mobility group box 1 (HMGB1), released from GSDMC‐mediated pyroptotic tumor cells, upregulates CXCL2 expression in adjacent tumor cells, thereby recruiting myeloid‐derived suppressor cells ...
Hanchao Gao, Yikun Yao, Weilong Li, Zigan Xu, Wenjun Hu, Kewang Luo, Peishan Chen, Wanjing Shang, Shaodong Luan, Guojun Shi, Mengtao Cao, Pengfei Chen   +11 more
wiley   +1 more source

Pre-existing Distortions in Nucleic Acid Structure Aid Polypurine Tract Selection by HIV-1 Reverse Transcriptase [PDF]

, 2002
Mamuka Kvaratskhelia, Scott R. Budihas, Stuart F.J. Le Grice   +2 more
openalex   +1 more source

Microneedles at the Forefront of Next Generation Theranostics

Advanced Science, EarlyView.
The TOC figure illustrates the revolutionary role of microneedles in modern medicine, showcasing their dual diagnostic and therapeutic functions. On the left, microneedles access interstitial fluid for real‐time monitoring of biomarkers like glucose and hormones.
Chan Wang, Yuan Yang, Jiaqi Zhang, Hanrui Zhang, Qian Wang, Shengmei Ma, Pengfei Zhao, Zhou Li, Yuxin Liu   +8 more
wiley   +1 more source

Cytidine protonation and base-pair intercalation in nucleic acid structures: The i-motif [PDF]

, 2002
J. L. Leroy
openalex   +1 more source

Structural flexibility in the ordered domain of the dengue virus strain 2 capsid protein is critical for chaperoning viral RNA replication. [PDF]

Cell Mol Life Sci
Sharma KK, Raghuvamsi PV, Aik DYK, Marzinek JK, Bond PJ, Wohland T.   +5 more
europepmc   +1 more source

Screening and Identification of Novel DNA Aptamer for Targeted Delivery to Injured Podocytes in Glomerular Diseases

Advanced Science, EarlyView.
This study develops RLS‐2, a high‐affinity aptamer that specifically targets injured podocytes, making it a promising candidate for targeted drug delivery. In vitro, RLS‐2 shows stability, specificity, efficient siRNA delivery via AsiCs, and uptake by podocytes.
Chao Zhou, Zhaofeng Luo, Zheng Zhang, Qing Ye, Dongjie Wang, Hanyan Meng, Jiayu Zhang, Shifan Zhu, Lidan Hu, Jianhua Mao   +9 more
wiley   +1 more source