Results 41 to 50 of about 737,876 (305)

HiTRACE: High-throughput robust analysis for capillary electrophoresis [PDF]

, 2011
Motivation: Capillary electrophoresis (CE) of nucleic acids is a workhorse technology underlying high-throughput genome analysis and large-scale chemical mapping for nucleic acid structural inference. Despite the wide availability of CE-based instruments,
Bylund, Cormen, Cover, Das, Das, Deigan, Ewing, Ewing, Hanjoo Kim, Jinkyu Kim, Justine Hum, Kay, Kazmi, Kladwang, Kladwang, Laederach, Levenberg, Marquardt, Merino, Mitra, Nielsen, Oppenheim, Peattie, Pravdova, Rhiju Das, Robinson, Ruiz-Martinez, Seunghyun Park, Sungroh Yoon, Tijerina, Tomasi, Vasa, Walczak, Watts, Weeks, Wilkinson, Wipapat Kladwang, Wong, Woolley, Xi   +39 more
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Increasing SARS-CoV-2 nucleic acid testing capacity during the COVID-19 epidemic in Beijing: experience from a general hospital

Emerging Microbes and Infections, 2020
Under the ongoing COVID-19 prevention and control measures in China, increasing the laboratory severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleic acid testing capacity has become the top priority.
Qi Wang, Xiaotao Zhao, Zhihong Yue, Xiaohui Bai, Huiying Rao, Na Han, Tianbing Wang, Hui Wang, Baoguo Jiang   +8 more
doaj   +1 more source

Modification mapping by nanopore sequencing

Frontiers in Genetics, 2022
Next generation sequencing (NGS) has provided biologists with an unprecedented view into biological processes and their regulation over the past 2 decades, fueling a wave of development of high throughput methods based on short read DNA and RNA ...
Laura K. White, Jay R. Hesselberth
doaj   +1 more source

Mining of Leaf Rust Resistance Genes Content in Egyptian Bread Wheat Collection

Plants, 2021
Wheat is a major nutritional cereal crop that has economic and strategic value worldwide. The sustainability of this extraordinary crop is facing critical challenges globally, particularly leaf rust disease, which causes endless problems for wheat ...
Mohamed A. M. Atia, Eman A. El-Khateeb, Reem M. Abd El-Maksoud, Mohamed A. Abou-Zeid, Arwa Salah, Amal M. E. Abdel-Hamid   +5 more
doaj   +1 more source

Dendrimers in gene delivery [PDF]

, 2005
Dendrimers have unique molecular architectures and properties that make them attractive materials for the development of nanomedicines. Key properties such as defined architecture and a high ratio of multivalent surface moieties to molecular volume also ...
Dufès, Christine, Schätzlein, Andreas G., Uchegbu, Ijeoma F.   +2 more
core   +1 more source

Strain-dependent porcine circovirus type 2 (PCV2) entry and replication in T-lymphoblasts [PDF]

, 2019
Porcine circovirus type 2 (PCV2) is the etiological agent of PCV2-associated diseases (PCVAD). PCV2 targets lymphoblasts, and pigs suffering from PCVAD display lymphocyte depletion in lymphoid tissues. PCV2 infection of lymphoblasts has not been studied.
Nauwynck, Hans, Van Renne, Nicolaas, Wei, Ruifang   +2 more
core   +1 more source

Developing Community Resources for Nucleic Acid Structures

Life, 2022
In this review, we describe the creation of the Nucleic Acid Database (NDB) at Rutgers University and how it became a testbed for the current infrastructure of the RCSB Protein Data Bank. We describe some of the special features of the NDB and how it has
Helen M. Berman, Catherine L. Lawson, Bohdan Schneider   +2 more
doaj   +1 more source

Crystal structure of the two-RRM domain of hnRNP A1 (UP1) complexed with single-stranded telomeric DNA [PDF]

, 1999
Human hnRNP A1 is a versatile single-stranded nucleic acid-binding protein that functions in various aspects of mRNA maturation and in telomere length regulation.
Ding, J. Z., Hayashi, M. K., Krainer, A. R., Manche, L., Xu, R. M., Zhang, Y.   +5 more
core   +2 more sources

Secondary structure formation of homopolymeric single-stranded nucleic acids including force and loop entropy: implications for DNA hybridization

, 2011
Loops are essential secondary structure elements in folded DNA and RNA molecules and proliferate close to the melting transition. Using a theory for nucleic acid secondary structures that accounts for the logarithmic entropy c ln m for a loop of length m,
Einert, Thomas R., Netz, Roland R., Orland, Henri   +2 more
core   +1 more source

Predicting nucleic acid binding interfaces from structural models of proteins [PDF]

, 2012
The function of DNA‐ and RNA‐binding proteins can be inferred from the characterization and accurate prediction of their binding interfaces. However, the main pitfall of various structure‐based methods for predicting nucleic acid binding function is that
Ahmad, Cazals, Charoensawan, Gao, Gao, Helles, Kanitz, Kinoshita, Liwo, Nimrod, Nimrod, Perez-Cano, Rigden, Roy, Shazman, Shazman, Shazman, Simons, Stawiski, Szilagyi, Thornton, Wu, Wu, Zhang, Zhang, Zhang, Zhao, Zhao   +27 more
core   +1 more source