Results 211 to 220 of about 34,814 (245)
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Protein-nucleic acid thermodynamic databases for specific uses.
Trends in biotechnology, 2023In response to Gromiha and Harini, we review the currently available thermodynamic databases for protein-nucleic acid interactions. These databases are designed for particular uses. We give general comments on them to facilitate browsing and exploration.
Long-Can, Mei +2 more
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A Spectroscopic and Thermodynamic Study of Taxol Nucleic Acid Complexes
Nucleosides and Nucleotides, 1999The interactions of natural and synthetic polynucleotide double strands with the antitumor agent paclitaxel and the oncological product "Taxol for Injection Concentrate" (abbreviated as taxol) were examined in diluted aqueous solutions by thermal denaturation profiles (Tm), CD spectra and UV-absorption measurements.
G, Bischoff +4 more
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Thermodynamic databases for proteins and protein-nucleic acid interactions
Biopolymers, 2001Thermodynamic data regarding proteins and their interactions are important for understanding the mechanisms of protein folding, protein stability, and molecular recognition. Although there are several structural databases available for proteins and their complexes with other molecules, databases for experimental thermodynamic data on protein stability ...
A, Sarai +7 more
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A Mathematical Model of Nucleic Acid Thermodynamics
2018The DNA denaturation, the double-stranded DNA unwinding process, is a vital process for cells. The percentage of the denaturation is used as an index of organism complexity and it is the base of the DNA hybridisation technique, which provides a great deal of information.
Sonia Guarguagli, Franco Pastrone
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The Thermodynamic Basis of the Stability of Proteins, Nucleic Acids, and Membranes
1976Publisher Summary The contributions of the polar and nonpolar components of the proteins and nucleic acids can be regarded as constituting the bricks and mortar, respectively, of the two structures. This chapter describes the changes in enthalpy and entropy of reactions as diverse as denaturation, ligand binding, and self-association display a ...
H, Edelhoch, J C, Osborne
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Analyzing and predicting the thermodynamic effects of the metabolite trehalose on nucleic acids
Biopolymers, 2010AbstractThere is a lot of interest in exactly how nucleic acid duplexes are affected by the addition of certain stabilizing and destabilizing metabolites. Unfortunately, the differences in reaction conditions between published reports often precludes a comparison of the results, effectively preventing a cohesive strategy for predicting additive effects
Jonathan L, Hart +2 more
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Biopolymers, 2000
The dissociation and assembly of quadruplex DNA structures (and a few quadruplex RNAs) have been characterized at several levels of rigor, ranging from gross descriptions of factors that govern each process, to semiquantitative comparisons of the relative abilities of these factors to induce stabilization or destabilization, to quantitative studies of ...
C C, Hardin, A G, Perry, K, White
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The dissociation and assembly of quadruplex DNA structures (and a few quadruplex RNAs) have been characterized at several levels of rigor, ranging from gross descriptions of factors that govern each process, to semiquantitative comparisons of the relative abilities of these factors to induce stabilization or destabilization, to quantitative studies of ...
C C, Hardin, A G, Perry, K, White
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Computer Methods and Programs in Biomedicine, 2013
Proper design of nucleic acid sequences is crucial for many applications. We have previously established a thermodynamics-based quantitative model to help design aptamer-based nucleic acid probes by predicting equilibrium concentrations of all interacting species.
Jiaqi Zou, Na Li
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Proper design of nucleic acid sequences is crucial for many applications. We have previously established a thermodynamics-based quantitative model to help design aptamer-based nucleic acid probes by predicting equilibrium concentrations of all interacting species.
Jiaqi Zou, Na Li
exaly +3 more sources
Kinetic and Thermodynamic Origins of Osmolyte-Influenced Nucleic Acid Folding
The Journal of Physical Chemistry B, 2015The influential role of monovalent and divalent metal cations in facilitating conformational transitions in both RNA and DNA has been a target of intense biophysical research efforts. However, organic neutrally charged cosolutes can also significantly alter nucleic acid conformational transitions.
Erik D, Holmstrom +2 more
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Synthesis and thermodynamics of peptide nucleic acid-conjugates
2023Submission note: A thesis submitted in total fulfilment of the requirements for the degree of Doctor of Philosophy to the School of Molecular Sciences, Faculty of Science Technology and Engineering, La Trobe University, Bundoora.
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