Results 201 to 210 of about 34,814 (245)
Advances in Isotope Labeling for Solution Nucleic Acid Nuclear Magnetic Resonance Spectroscopy. [PDF]
Hilber S +3 more
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Modulating transformation of DNA origami nanoarray via sequence design. [PDF]
Wang D +6 more
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Thermodynamics of Nucleic Acid “Shape Readout” by an Aminosugar [PDF]
Recognition of nucleic acids is important for our understanding of nucleic acid structure as well as for our understanding of nucleic acid-protein interactions. In addition to the direct readout mechanisms of nucleic acids such as H-bonding, shape recognition of nucleic acids is being increasingly recognized as playing an equally important role in DNA ...
Nihar Ranjan, Liang Xue, Dev P Arya
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Thermodynamic database supports deciphering protein–nucleic acid interactions
Trends in Biotechnology, 2023The thermodynamics of protein-nucleic acid interactions (PNIs) is crucial for elucidating the mechanisms of molecular recognition and pathological consequences. The Protein-Nucleic Acid Thermodynamics Database (PNATDB) is a database containing experimentally determined thermodynamic parameters along with sequence, structural, and function data, which ...
Long-Can Mei +2 more
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Thermodynamics of ligand-nucleic acid interactions.
Methods in enzymology, 1992Ligand-and protein-DNA equilibria are extremely sensitive to solution conditions (e.g., salt, temperature, and pH), and, in general, the effects of different solution variables are interdependent (i.e., linked). As a result, an assessment of the basis for the stability and specificity of ligand-or protein-DNA interactions requires quantitative studies ...
T M, Lohman, D P, Mascotti
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Thermodynamics of nucleic acids and their interactions with ligands
Quarterly Reviews of Biophysics, 20001. Introduction 2551.1 General thermodynamics 2562. Nucleic acid thermodynamics 2602.1 DNA duplexes 2612.2 RNA duplexes 2632.3 Hybrid DNA–RNA duplexes 2642.4 Hydration 2672.5 Conformational flexibility 2692.6 Thermodynamics 2723. Nucleic acid–ligand interactions 2773.1 Minor groove binders 2783.2 DNA intercalators 2843.3 Triple-helical systems 2883.3.1
A N, Lane, T C, Jenkins
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Thermodynamic study of hybridization properties of heterochiral nucleic acids
Biochemical and Biophysical Research Communications, 2003Heterochiral DNA and RNA heptamers, which contained an unnatural L-nucleotide, were synthesized, and thermodynamic analyses of their hybridization properties with complementary DNA and RNA strands were systematically conducted by UV melting experiments.
Hidehito, Urata +4 more
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Quantitative nucleic acids footprinting: thermodynamic and kinetic approaches
Current Opinion in Biotechnology, 1997Quantitative footprinting techniques allow a detailed analysis of the thermodynamic forces that characterize nucleic acid-ligand interactions and ligand-induced changes in nucleic acid structure by separately resolving the intrinsic and cooperative Gibbs free energy changes describing the reactions being investigated.
V, Petri, M, Brenowitz
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Thermodynamic Characterization of Nucleic Acid Nanoparticles Hybridization by UV Melting
2023The advances in nucleic acid nanotechnology have given rise to various elegantly designed structural complexes fabricated from DNA, RNA, chemically modified RNA strands, and their mixtures. The structural properties of NA nanoparticles (NANP) generally dictate and significantly impact biological function; and thus, it is critical to extract information
Megan, Teter +3 more
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