Results 201 to 210 of about 34,814 (245)

Modulating transformation of DNA origami nanoarray via sequence design. [PDF]

open access: yesNat Commun
Wang D   +6 more
europepmc   +1 more source

Thermodynamics of Nucleic Acid “Shape Readout” by an Aminosugar [PDF]

open access: yesBiochemistry, 2011
Recognition of nucleic acids is important for our understanding of nucleic acid structure as well as for our understanding of nucleic acid-protein interactions. In addition to the direct readout mechanisms of nucleic acids such as H-bonding, shape recognition of nucleic acids is being increasingly recognized as playing an equally important role in DNA ...
Nihar Ranjan, Liang Xue, Dev P Arya
exaly   +3 more sources
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Thermodynamic database supports deciphering protein–nucleic acid interactions

Trends in Biotechnology, 2023
The thermodynamics of protein-nucleic acid interactions (PNIs) is crucial for elucidating the mechanisms of molecular recognition and pathological consequences. The Protein-Nucleic Acid Thermodynamics Database (PNATDB) is a database containing experimentally determined thermodynamic parameters along with sequence, structural, and function data, which ...
Long-Can Mei   +2 more
exaly   +3 more sources

Thermodynamics of ligand-nucleic acid interactions.

Methods in enzymology, 1992
Ligand-and protein-DNA equilibria are extremely sensitive to solution conditions (e.g., salt, temperature, and pH), and, in general, the effects of different solution variables are interdependent (i.e., linked). As a result, an assessment of the basis for the stability and specificity of ligand-or protein-DNA interactions requires quantitative studies ...
T M, Lohman, D P, Mascotti
openaire   +2 more sources

Thermodynamics of nucleic acids and their interactions with ligands

Quarterly Reviews of Biophysics, 2000
1. Introduction 2551.1 General thermodynamics 2562. Nucleic acid thermodynamics 2602.1 DNA duplexes 2612.2 RNA duplexes 2632.3 Hybrid DNA–RNA duplexes 2642.4 Hydration 2672.5 Conformational flexibility 2692.6 Thermodynamics 2723. Nucleic acid–ligand interactions 2773.1 Minor groove binders 2783.2 DNA intercalators 2843.3 Triple-helical systems 2883.3.1
A N, Lane, T C, Jenkins
openaire   +2 more sources

Thermodynamic study of hybridization properties of heterochiral nucleic acids

Biochemical and Biophysical Research Communications, 2003
Heterochiral DNA and RNA heptamers, which contained an unnatural L-nucleotide, were synthesized, and thermodynamic analyses of their hybridization properties with complementary DNA and RNA strands were systematically conducted by UV melting experiments.
Hidehito, Urata   +4 more
openaire   +2 more sources

Quantitative nucleic acids footprinting: thermodynamic and kinetic approaches

Current Opinion in Biotechnology, 1997
Quantitative footprinting techniques allow a detailed analysis of the thermodynamic forces that characterize nucleic acid-ligand interactions and ligand-induced changes in nucleic acid structure by separately resolving the intrinsic and cooperative Gibbs free energy changes describing the reactions being investigated.
V, Petri, M, Brenowitz
openaire   +2 more sources

Thermodynamic Characterization of Nucleic Acid Nanoparticles Hybridization by UV Melting

2023
The advances in nucleic acid nanotechnology have given rise to various elegantly designed structural complexes fabricated from DNA, RNA, chemically modified RNA strands, and their mixtures. The structural properties of NA nanoparticles (NANP) generally dictate and significantly impact biological function; and thus, it is critical to extract information
Megan, Teter   +3 more
openaire   +2 more sources

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