Results 201 to 210 of about 2,687,425 (254)
Buffer and salt dependent reassembly pathways of Myxococcus xanthus encapsulin
Abstract Protein cages that adopt multiple assembly states provide tractable systems for probing the mechanisms that govern icosahedral shell formation. The Myxococcus xanthus encapsulin shell protein assembles into either a T = 1 shell (60 subunits) or a T = 3 shell (180 subunits), making it an ideal model to investigate how solution conditions bias ...
Varnika Yadav, Tobias Beck
wiley +1 more source
RNA•DNA:DNA triplex formation by <i>HIF1α-AS1</i> modulates individual base pair stabilities in the <i>adrenomedullin</i> DNA target duplex. [PDF]
Krause NM +5 more
europepmc +1 more source
ProNIT: Thermodynamic Database for Protein-Nucleic Acid Interactions
Prabakaran, P. +6 more
openaire +1 more source
Programming Multidomain Peptides With Molecular Frustration Into Biomolecular Condensates
De novo designed multidomain peptides (MDPs) were used to explore how molecular ordering influences peptide phase behavior. MDPs containing partially folded β‐sheets were found to form biomolecular condensates. This work introduces a new design principle for condensate formation and expand the design space beyond conventional intrinsically disordered ...
Debdatta Das +12 more
wiley +1 more source
Viruses under mechanical force: Implications and applications. [PDF]
Mateu MG.
europepmc +1 more source
Electrostatic topology is shown to program phase separation and internal organization in thermoresponsive intrinsically disordered protein polymer (IDPP) condensates. By comparing oppositely charged IDPPs with a covalent diblock, chain connectivity is revealed to control charge compensation, dense‐phase micropolarity, miscibility, and apparent acid ...
Julio Fernández‐Fernández +6 more
wiley +1 more source
Molecular Dissipative Structuring: The Fundamental Creative Force in Biology. [PDF]
Michaelian K.
europepmc +1 more source
Artificial dissipative systems typically operate under batchwise fuel additions into closed reactors, leading to only transient nonequilibrium states. Alternative fueling approaches show how moving toward thermodynamically open conditions, sustained fuel supply, and reaction‐diffusion control provide enhanced regulation of self‐assembly and access to ...
James D. Nicholas +4 more
wiley +1 more source
Accurately modeling RNase H-mediated antisense oligonucleotide efficacy. [PDF]
Hill B +9 more
europepmc +1 more source

