Results 181 to 190 of about 34,814 (245)

Modeling biomolecular condensates across scales: Atomistic, coarse-grained, and data-driven approaches. [PDF]

Adv Phys X
Maristany MJ, Emelianova A, Chew PY, Aguirre A, Collepardo-Guevara R, Joseph JA.   +5 more
europepmc   +1 more source

SARS‐CoV‐2 nucleocapsid protein variants have differential RNA chaperone activity

The FEBS Journal, Volume 293, Issue 9, Page 2579-2598, May 2026.
The SARS‐CoV‐2 nucleocapsid (N) protein is not only the specific viral RNA packaging protein, but also acts as an RNA chaperone, facilitating RNA folding. We show that it facilitates RNA annealing through its RBD–IDR2–CTD region, identifying it as a functional RNA chaperone.
Sabrina Babl, Julia M. Seidel, Fabian Kugler, Elisabeth Silberhorn, Anna Ludwig, Jonas Abel, Sophia Winklbauer, Niklas Schaub, Silvia Materna‐Reichelt, Kamran Honarnejad, Nataša Stojanović Gužvić, Gernot Längst   +11 more
wiley   +1 more source

Aptamer Engineering: Strategies for Discovering Functional Nucleic Acids for Next-Generation Diagnostics and Biosensing. [PDF]

Adv Sci (Weinh)
Nguyen JVL, Meziadi A, Brunner C, McKeague M, Malic L, Tabrizian M.   +5 more
europepmc   +1 more source

Characterisation of a cold‐adapted, thermostable glucokinase from psychrophilic Pseudoalteromonas sp. AS‐131 reveals how the enzyme achieves high thermal stability without loss of cold adaptation

The FEBS Journal, Volume 293, Issue 9, Page 2617-2636, May 2026.
We investigated glucokinase from the psychrophilic Pseudoalteromonas sp. AS‐131 (PsGK), which was isolated from the Antarctic Ocean. Biochemical studies revealed that PsGK is a cold‐adapted enzyme with high thermal stability, in contrast to general cold‐adapted enzymes, which have low thermal stability.
Akane Yato, Yuki Kato, Fuyuko Hayashi, Rio Asaka, Atsuko Ogawa, Tokuro Oda, Sayaka Tsuji, Masashi Unno, Nobuaki Soh, Keiichi Watanabe, Masaki Horitani   +10 more
wiley   +1 more source

A RPA-CRISPR/Cas12a-Powered Catalytic Hairpin Assembly Fluorescence Biosensor for Duck Plague Virus Virulent Strain Detection. [PDF]

Biosensors (Basel)
Wu Y, Wan J, Wang X, Shen Y, Li X, Zhou W, Zhu Y, Xu X.   +7 more
europepmc   +1 more source

Lipid‐Based Nanoparticles for Time‐Release Delivery of Flavonoids

Journal of Food Process Engineering, Volume 49, Issue 5, May 2026.
Lipid‐based nanocarriers enhance the stability, bioavailability, and controlled release of flavonoids. These systems improve encapsulation efficiency and protection against degradation, highlighting their potential for food and nutraceutical applications.
Ziane da Conceição das Mercês, Viviani Ruffo de Oliveira, Simone Hickmann Flôres, Alessandro de Oliveira Rios   +3 more
wiley   +1 more source

Structure-based Discovery of a Non-competitive FTO Inhibitor Bound to a Cryptic Site at the Domain Interface. [PDF]

J Mol Biol
Singh A, Pettini F, Gianibbi B, Das S, Barisani D, Purslow JA, Furini S, Spiga O, Venditti V.   +8 more
europepmc   +1 more source

Tomato Spotted Wilt Virus Reprogrammes Host Glycolysis to Facilitate Proliferation by a Phase‐Separated Co‐Aggregate of Nucleocapsid Protein and Phosphoglycerate Kinase

Plant Biotechnology Journal, Volume 24, Issue 5, Page 2826-2842, May 2026.
ABSTRACT Efficient viral proliferation within the host is a critical step in pathogenicity and requires adenosine triphosphate (ATP). The replication, movement and immune evasion of many plant viruses within their hosts are associated with phase separation (PS)‐derived aggregates formed by viral components.
Guangcheng Zu, Zhifu Xing, Jiao Li, Tangbing Yang, Huan Wu, Qiangsheng Ge, Yanju Wang, Baoan Song, Runjiang Song   +8 more
wiley   +1 more source

A vital question-how to define inside and outside. [PDF]

Protoplasma
Nick P.
europepmc   +1 more source

Advances and opportunities for computational interrogation of plant proteins

The Plant Journal, Volume 126, Issue 3, May 2026.
SUMMARY Plants exhibit remarkable biochemical and physiological diversity, and are capable of adapting to a wide range of environmental conditions and stresses. This complexity makes them essential systems for understanding how life responds to a changing climate.
Sarah M. Bohling, Shaila Musharoff, Laura H. Gunn   +2 more
wiley   +1 more source