Results 171 to 180 of about 10,354 (218)

A universal and orthogonal safety valve for CRISPR/Cas12a without chemical modification or external stimulation. [PDF]

open access: yesNucleic Acids Res
Luo W   +14 more
europepmc   +1 more source

Thermodynamics of Nucleic Acid “Shape Readout” by an Aminosugar [PDF]

open access: yesBiochemistry, 2011
Recognition of nucleic acids is important for our understanding of nucleic acid structure as well as for our understanding of nucleic acid-protein interactions. In addition to the direct readout mechanisms of nucleic acids such as H-bonding, shape recognition of nucleic acids is being increasingly recognized as playing an equally important role in DNA ...
Nihar Ranjan, , Dev P Arya
exaly   +3 more sources
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Thermodynamic database supports deciphering protein–nucleic acid interactions

Trends in Biotechnology, 2023
The thermodynamics of protein-nucleic acid interactions (PNIs) is crucial for elucidating the mechanisms of molecular recognition and pathological consequences. The Protein-Nucleic Acid Thermodynamics Database (PNATDB) is a database containing experimentally determined thermodynamic parameters along with sequence, structural, and function data, which ...
Long-Can Mei   +2 more
exaly   +3 more sources

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