Results 221 to 230 of about 34,814 (245)
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THERMODYNAMIC PROFILE OF INTERACTION OF PORPHYRINS WITH NUCLEIC ACIDS

2007
The binding of a number of novel water soluble porphyrins to nucleic acids (NA) were studied monitoring the changes in Soret region of absorbance spectra, fluorescence spectra and circular dichroism (CD) spectra of formed complexes. The binding modes for all complexes were dtermined. The binding isotherms were used to calculate the binding constant, Kb,
Samvel Haroutiunian   +3 more
openaire   +1 more source

[Thermodynamic models of binding ligands to nucleic acids].

Biofizika, 2004
Models of adsorption were considered, which describe the binding of biologically active ligands on DNA templates. The binding is described most comprehensively and in greatest detail by the distribution function, which determines the probability of detecting the preset number of adsorbed ligands on the template.
Iu D, Nechipurenko, G V, Gurskii
openaire   +1 more source

Thermodynamics of Nucleic Acids Enclosed in Reverse Phase Vesicles

1984
Reverse micelles and vesicles mimic properties of biological membranes in the sense that they include a small water volume in a charged or in an at least polar surface formed by the hydrophilic headgroups of amphiphilic compounds. Membranes with this type of a surface form the cellular compartments which are the reaction vessels for most chemical ...
Bernhard Brosius   +3 more
openaire   +1 more source

Thermodynamic Studies of Amsacrine Antitumor Agents with Nucleic Acids

1990
The equilibrium binding of several anilinoacridine analogs are compared over a wide range of ionic strengths and temperatures. Although o-AMSA binds DNA with a higher affinity than m-AMSA it is not effective as an antitumor agent. Both m-AMSA and o-AMSA bind DNA in an intercalative manner.
D. E. Graves, R. M. Wadkins
openaire   +1 more source

[Thermodynamic characteristics of nucleic acid complexes with silver ions].

Biofizika, 1981
By means of mixing reaction calorimetry the enthalpy of the complexes formation between Ag+ ions and DNA and dsRNA was measured. It was shown that Ag+ ions are able to form two types of complexes (I and II) with dsRNA. Using the method of the competitive reaction with chloride ions the stability constants of complex formation were obtained for dsRNA-Ag+
K A, Minasian   +2 more
openaire   +1 more source

Nucleic Acid Tests for Clinical Translation

Chemical Reviews, 2021
Min Li, Fangfei Yin, Lu Song
exaly  

Molecular modeling and thermodynamics simulation of nucleic acids

2016
Nucleic acids participate in many cellular processes. DNA is responsible for gene heredity and its structure is mainly in double helix, whereas RNA has wide functions in gene transcription and regulation so its structures are varied among species.
openaire   +1 more source

Self-Assembling Nucleic Acid Nanostructures Functionalized with Aptamers

Chemical Reviews, 2021
Abhichart Krissanaprasit   +2 more
exaly  

DNA Probes: Applications of the Principles of Nucleic Acid Hybridization

Critical Reviews in Biochemistry and Molecular Biology, 1991
James G Wetmur
exaly  

Insight into the High Duplex Stability of the Simplified Nucleic Acid GNA

Angewandte Chemie - International Edition, 2009
Mark K Schlegel   +2 more
exaly  

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