Results 91 to 100 of about 7,455 (179)
Nucleic and Amino Acid Sequences Support Structure-Based Viral Classification [PDF]
, 2017 Viral capsids ensure viral genome integrity by protecting the enclosed nucleic acids. Interactions between the genome and capsid and between individual capsid proteins (i.e., capsid architecture) are intimate and are expected to be characterized by ...
Bamford, Dennis H. +2 more
core +2 more sources
Advanced Science, Volume 12, Issue 45, December 4, 2025.The TMEM43 ‐ P386S mutation causes arrhythmogenic right ventricular cardiomyopathy (ARVC) by mislocalizing itself from nuclear envelope (NE) to cytoplasm, disrupting lamin B2 (a novel TMEM43 interactor) localization, NE integrity and chromatin accessibility, causing hyper ‐ phosphorylation and reduced expression/clustering of ryanodine receptor type 2 (
Jiaxi Shen +23 more
wiley +1 more source
The multifunctional NS1 protein of influenza A viruses [PDF]
, 2012 The non-structural (NS1) protein of influenza A viruses is a non-essential virulence factor that has multiple accessory functions during viral infection.
Hale, Benjamin Geoffrey +3 more
core +1 more source
Cancer Communications, Volume 45, Issue 12, Page 1676-1705, December 2025.Abstract Background Brain metastasis, a leading cause of death in patients with lung adenocarcinoma (LUAD), arises from tumor cells adapting to the unique microenvironment of the brain through metabolic remodeling regulated by key oncogenes. Here, we aimed to determine the role of high mobility group protein box 3 (HMGB3) in regulating tumor cell ...
Huanhuan Cui +12 more
wiley +1 more source
Effects of hypo O-GlcNAcylation on Drosophila development [PDF]
, 2018 Post-translational modification of serine/threonine residues in nucleocytoplasmic proteins with N-acetylglucosamine (OGlcNAcylation) is an essential regulatory mechanism in many cellular processes.
Andrew T. Ferenbach +76 more
core +3 more sources
Clinical and Translational Medicine, Volume 15, Issue 12, December 2025.We established a robust predictive model for nasopharyngeal carcinoma (NPC) distant metastasis using RNA markers. When combined with clinical parameters, our RNA‐based risk score significantly improved the area under the curve to 90.4%. This study revealed that tertiary lymphoid structure formation may be associated with lower NPC metastasis risk after
Zhaozheng Hou +16 more
wiley +1 more source
Pithovirus sibericum, a new bona fide member of the Fourth TRUC club
Frontiers in Microbiology, 2015 Nucleocytoplasmic large DNA viruses, or representatives of the proposed order Megavirales, include giant viruses of Acanthamoeba that were discovered over the last 12 years and are bona fide microbes.
Vikas eSharma +7 more
doaj +1 more source
Two New Sturgeon Species are Susceptible to Acipenser Iridovirus European (AcIV-E) Infection
Pathogens, 2020 We report the first case of Acipenser iridovirus European (AcIV-E) infection in starry sturgeon (Acipenser stellatus) and in sterlet (A. ruthenus) reared in Northern Italy. During 2018, mortality began in A. stellatus and A.
Davide Mugetti +7 more
doaj +1 more source
Generation of recombinant influenza A virus without M2 ion-channel protein by introduction of a point mutation at the 5′ end of the viral intron [PDF]
, 2005 The aim of this study was to inhibit influenza virus M2 protein expression by mutating the splicing signal of the M gene. Mutations were introduced into the GU dinucleotide sequence at the 5′-proximal splicing site of the M gene (corresponding to nt 52 ...
Chen, H +6 more
core +1 more source
MedComm, Volume 6, Issue 12, December 2025.Protein arginine methyltransferase 1 (PRMT1) is a pivotal enzyme that catalyzes the asymmetric dimethylation of arginine residues, thereby functioning as a critical epigenetic regulator of diverse biological processes such as gene expression, RNA splicing, and DNA repair.
Yanqun Luo +4 more
wiley +1 more source