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Codon usage of human DNA viruses and its similarity to certain host genes [PDF]

open access: yesScientific Reports
Codon usages of DNA viruses had previously been shown to associate with their genome size. Codon usage of various human DNA viruses was compared to those of human genes to further understand viral codon usage and its roles in viral-host interaction ...
Thanyaporn Sirihongthong   +4 more
doaj   +2 more sources

Tumor Tropism of DNA Viruses for Oncolytic Virotherapy [PDF]

open access: yesViruses, 2023
Oncolytic viruses (OVs) have emerged as one of the most promising cancer immunotherapy agents that selectively target and kill cancer cells while sparing normal cells. OVs are from diverse families of viruses and can possess either a DNA or an RNA genome.
Junior A. Enow   +2 more
doaj   +2 more sources

A chemical method for generating live-attenuated, replication-defective DNA viruses for vaccine development

open access: yesCell Reports: Methods, 2022
Summary: The development of a chemically attenuated, replication-incompetent virus vaccine can provide protection against diseases caused by DNA viruses.
Dabbu Kumar Jaijyan   +3 more
doaj   +3 more sources

Pervasive Chimerism in the Replication-Associated Proteins of Uncultured Single-Stranded DNA Viruses

open access: yesViruses, 2018
Numerous metagenomic studies have uncovered a remarkable diversity of circular replication-associated protein (Rep)-encoding single-stranded (CRESS) DNA viruses, the majority of which are uncultured and unclassified. Unlike capsid proteins, the Reps show
Darius Kazlauskas   +2 more
doaj   +3 more sources

Activation of the DNA Damage Response by RNA Viruses

open access: yesBiomolecules, 2016
RNA viruses are a genetically diverse group of pathogens that are responsible for some of the most prevalent and lethal human diseases. Numerous viruses introduce DNA damage and genetic instability in host cells during their lifecycles and some species ...
Ellis L. Ryan   +2 more
doaj   +3 more sources

Sensing Viruses by Mechanical Tension of DNA in Responsive Hydrogels

open access: yesPhysical Review X, 2014
The rapid worldwide spread of severe viral infections, often involving novel mutations of viruses, poses major challenges to our health-care systems. This means that tools that can efficiently and specifically diagnose viruses are much needed.
Jaeoh Shin   +2 more
doaj   +3 more sources

Identification and characterization of novel CRESS-DNA viruses in the human respiratory tract [PDF]

open access: yesVirology Journal
CRESS-DNA viruses are small, circular, single-stranded DNA viruses that have been identified in diverse environments and hosts, including vertebrates, invertebrates, and environmental samples.
Huanyan Zhang   +6 more
doaj   +2 more sources

Interactions between Autophagy and DNA Viruses

open access: yesViruses, 2019
Autophagy is a catabolic biological process in the body. By targeting exogenous microorganisms and aged intracellular proteins and organelles and sending them to the lysosome for phagocytosis and degradation, autophagy contributes to energy recycling ...
Hai-chang Yin   +5 more
doaj   +3 more sources

The Intricate Interplay between APOBEC3 Proteins and DNA Tumour Viruses

open access: yesPathogens
APOBEC3 proteins are cytidine deaminases that play a crucial role in the innate immune response against viruses, including DNA viruses. Their main mechanism for restricting viral replication is the deamination of cytosine to uracil in viral DNA during ...
Nika Lovšin   +2 more
doaj   +3 more sources

Genetic Phylocomparative Analysis of B2L, F1L Genes in Orf Virus Isolated from Felid Infected Sheep [PDF]

open access: yesBasrah Journal of Veterinary Research, 2023
Contagious ecthyma virus Large, oval, double-stranded DNA viruses from the family Poxviridae they are distinct from other poxviruses due to their unusual spiral coat.  Orf virus encoded highly conserved F1L gene, B2L gene, which codes for highly ...
Khetam Mayea, Hazim Thwiny, Hayder Ayyez
doaj   +1 more source

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