Results 1 to 10 of about 376,461 (219)

RNA Structures and Their Role in Selective Genome Packaging

open access: yesViruses, 2021
To generate infectious viral particles, viruses must specifically select their genomic RNA from milieu that contains a complex mixture of cellular or non-genomic viral RNAs.
Liqing Ye   +7 more
doaj   +1 more source

Interactions of the Insect-Specific Palm Creek Virus with Zika and Chikungunya Viruses in Aedes Mosquitoes

open access: yesMicroorganisms, 2021
Palm Creek virus (PCV) is an insect-specific flavivirus that can interfere with the replication of mosquito-borne flaviviruses in Culex mosquitoes, thereby potentially reducing disease transmission.
Cassandra Koh   +3 more
doaj   +1 more source

Hidden Viral Sequences in Public Sequencing Data and Warning for Future Emerging Diseases

open access: yesmBio, 2021
RNA viruses cause numerous emerging diseases, mostly due to transmission from mammalian and avian reservoirs. Large-scale surveillance of RNA viral infections in these animals is a fundamental step for controlling viral infectious diseases.
Junna Kawasaki   +3 more
doaj   +1 more source

The Railmap of Type I Interferon Induction: Subcellular Network Plan and How Viruses Can Change Tracks

open access: yesCells, 2022
The innate immune response constitutes the cell’s first line of defense against viruses and culminates in the expression of type I interferon (IFN) and IFN-stimulated genes, inducing an antiviral state in infected and neighboring cells.
Laura Weber, Gabrielle Vieyres
doaj   +1 more source

Evidence For Long-Lasting Transgenerational Antiviral Immunity in Insects

open access: yesCell Reports, 2020
Summary: Transgenerational immune priming (TGIP) allows memory-like immune responses to be transmitted from parents to offspring in many invertebrates.
Juan A. Mondotte   +8 more
doaj   +1 more source

Reverse Genetics and Artificial Replication Systems of Borna Disease Virus 1

open access: yesViruses, 2022
Borna disease virus 1 (BoDV-1) is a neurotropic RNA virus belonging to the family Bornaviridae within the order Mononegavirales. Whereas BoDV-1 causes neurological and behavioral disorders, called Borna disease (BD), in a wide range of mammals, its ...
Takehiro Kanda, Keizo Tomonaga
doaj   +1 more source

Intranasal murine pneumonia virus-vectored SARS-CoV-2 vaccine induces mucosal and serum antibodies in macaques

open access: yesiScience, 2023
Summary: Next-generation SARS-CoV-2 vaccines are needed that induce systemic and mucosal immunity. Murine pneumonia virus (MPV), a murine homolog of respiratory syncytial virus, is attenuated by host-range restriction in nonhuman primates and has a ...
Jaclyn A. Kaiser   +14 more
doaj   +1 more source

Differential Small RNA Responses against Co-Infecting Insect-Specific Viruses in Aedes albopictus Mosquitoes

open access: yesViruses, 2020
The mosquito antiviral response has mainly been studied in the context of arthropod-borne virus (arbovirus) infection in female mosquitoes. However, in nature, both female and male mosquitoes are frequently infected with insect-specific viruses (ISVs ...
Lionel Frangeul   +3 more
doaj   +1 more source

Enhanced neutralization escape to therapeutic monoclonal antibodies by SARS-CoV-2 omicron sub-lineages

open access: yesiScience, 2023
Summary: The landscape of SARS-CoV-2 variants dramatically diversified with the simultaneous appearance of multiple subvariants originating from BA.2, BA.4, and BA.5 Omicron sub-lineages. They harbor a specific set of mutations in the spike that can make
Franck Touret   +10 more
doaj   +1 more source

Multifaceted contributions of Dicer2 to arbovirus transmission by Aedes aegypti

open access: yesCell Reports, 2023
Summary: Arthropod-borne viruses (arboviruses) transmitted by Aedes aegypti mosquitoes are an increasing threat to global health. The small interfering RNA (siRNA) pathway is considered the main antiviral immune pathway of insects, but its effective ...
Sarah Hélène Merkling   +11 more
doaj   +1 more source

Home - About - Disclaimer - Privacy