Results 11 to 20 of about 376,511 (268)

RNA viruses in the sea [PDF]

open access: yesFEMS Microbiology Reviews, 2009
Viruses are ubiquitous in the sea and appear to outnumber all other forms of marine life by at least an order of magnitude. Through selective infection, viruses influence nutrient cycling, community structure, and evolution in the ocean. Over the past 20 years we have learned a great deal about the diversity and ecology of the viruses that constitute ...
Andrew S, Lang   +3 more
openaire   +2 more sources

RNA chaperones encoded by RNA viruses [PDF]

open access: yesVirologica Sinica, 2015
RNAs are functionally diverse macromolecules whose proper functions rely strictly upon their correct tertiary structures. However, because of their high structural flexibility, correct folding of RNAs is challenging and slow. Therefore, cells and viruses encode a variety of RNA remodeling proteins, including helicases and RNA chaperones. In RNA viruses,
Yang, Jie   +3 more
openaire   +2 more sources

Translation of Plant RNA Viruses [PDF]

open access: yesViruses, 2021
Plant RNA viruses encode essential viral proteins that depend on the host translation machinery for their expression. However, genomic RNAs of most plant RNA viruses lack the classical characteristics of eukaryotic cellular mRNAs, such as mono-cistron, 5′ cap structure, and 3′ polyadenylation.
Guowei Geng   +7 more
openaire   +3 more sources

RNA viruses and mutations

open access: yesUirusu, 2005
Actively replicating RNA viruses in nature are continually changing their genetic information by spontaneous mutations. These changes often result in alterations in immune-sensitivity, drug-sensitivity, cell-tropism, and host-range, causing uncontrollability of the pathogen and emerging/re-emerging infections. To better understand the virus changes and
SATO, Hironori, YOKOYAMA, Masaru
openaire   +3 more sources

The Diversity of Human RNA Viruses [PDF]

open access: yesFuture Virology, 2013
We still cannot answer the very basic question "how many kinds of RNA viruses are there?" even for those that infect humans. It is often suggested that there remains a large number of viruses in humans that we have not yet discovered or recognised, and that there is a much larger and rapidly evolving pool of potential new viruses in mammalian and avian
Mark E J, Woolhouse, Kyle, Adair
openaire   +2 more sources

Intranasal immunization with avian paramyxovirus type 3 expressing SARS-CoV-2 spike protein protects hamsters against SARS-CoV-2

open access: yesnpj Vaccines, 2022
Current vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are administered parenterally and appear to be more protective in the lower versus the upper respiratory tract.
Hong-Su Park   +17 more
doaj   +1 more source

Evolutionary Selection of the Nuclear Localization Signal in the Viral Nucleoprotein Leads to Host Adaptation of the Genus Orthobornavirus

open access: yesViruses, 2020
Adaptation of the viral life cycle to host cells is necessary for efficient viral infection and replication. This evolutionary process has contributed to the mechanism for determining the host range of viruses.
Ryo Komorizono   +4 more
doaj   +1 more source

Ribosomal RNA (rRNA) sequences from 33 globally distributed mosquito species for improved metagenomics and species identification

open access: yeseLife, 2023
Total RNA sequencing (RNA-seq) is an important tool in the study of mosquitoes and the RNA viruses they vector as it allows assessment of both host and viral RNA in specimens. However, there are two main constraints.
Cassandra Koh   +9 more
doaj   +1 more source

In vivo biodistribution analysis of transmission competent and defective RNA virus-based episomal vector

open access: yesScientific Reports, 2020
RNA virus-based episomal vector (REVec) is an emerging viral vector system that mediates long-term stable gene expression in variety of cell types in vitro.
Yumiko Komatsu   +3 more
doaj   +1 more source

SARS‐CoV‐2 Omicron emergence urges for reinforced One‐Health surveillance

open access: yesEMBO Molecular Medicine, 2022
Graphical Abstract SARS‐CoV‐2 Omicron harbors substitutions in the receptor binding domain of the spike which strongly suggest its capacity to infect rodents.
Xavier Montagutelli   +3 more
doaj   +1 more source

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