Results 11 to 20 of about 377,054 (268)
RNA chaperones encoded by RNA viruses [PDF]
Virologica Sinica, 2015 RNAs are functionally diverse macromolecules whose proper functions rely strictly upon their correct tertiary structures. However, because of their high structural flexibility, correct folding of RNAs is challenging and slow. Therefore, cells and viruses encode a variety of RNA remodeling proteins, including helicases and RNA chaperones. In RNA viruses,
Yang, Jie +3 more
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Uirusu, 2005 Actively replicating RNA viruses in nature are continually changing their genetic information by spontaneous mutations. These changes often result in alterations in immune-sensitivity, drug-sensitivity, cell-tropism, and host-range, causing uncontrollability of the pathogen and emerging/re-emerging infections. To better understand the virus changes and
SATO, Hironori, YOKOYAMA, Masaru
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Multifaceted contributions of Dicer2 to arbovirus transmission by Aedes aegypti
Cell Reports, 2023 Summary: Arthropod-borne viruses (arboviruses) transmitted by Aedes aegypti mosquitoes are an increasing threat to global health. The small interfering RNA (siRNA) pathway is considered the main antiviral immune pathway of insects, but its effective ...
Sarah Hélène Merkling +11 more
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The Diversity of Human RNA Viruses [PDF]
Future Virology, 2013 We still cannot answer the very basic question "how many kinds of RNA viruses are there?" even for those that infect humans. It is often suggested that there remains a large number of viruses in humans that we have not yet discovered or recognised, and that there is a much larger and rapidly evolving pool of potential new viruses in mammalian and avian
Mark E J, Woolhouse, Kyle, Adair
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Translation of Plant RNA Viruses [PDF]
Viruses, 2021 Plant RNA viruses encode essential viral proteins that depend on the host translation machinery for their expression. However, genomic RNAs of most plant RNA viruses lack the classical characteristics of eukaryotic cellular mRNAs, such as mono-cistron, 5′ cap structure, and 3′ polyadenylation.
Guowei Geng +7 more
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npj Vaccines, 2022 Current vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are administered parenterally and appear to be more protective in the lower versus the upper respiratory tract.
Hong-Su Park +17 more
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eLife, 2023 Total RNA sequencing (RNA-seq) is an important tool in the study of mosquitoes and the RNA viruses they vector as it allows assessment of both host and viral RNA in specimens. However, there are two main constraints.
Cassandra Koh +9 more
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Scientific Reports, 2020 RNA virus-based episomal vector (REVec) is an emerging viral vector system that mediates long-term stable gene expression in variety of cell types in vitro.
Yumiko Komatsu +3 more
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Viruses, 2020 Adaptation of the viral life cycle to host cells is necessary for efficient viral infection and replication. This evolutionary process has contributed to the mechanism for determining the host range of viruses.
Ryo Komorizono +4 more
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SARS‐CoV‐2 Omicron emergence urges for reinforced One‐Health surveillance
EMBO Molecular Medicine, 2022 Graphical Abstract SARS‐CoV‐2 Omicron harbors substitutions in the receptor binding domain of the spike which strongly suggest its capacity to infect rodents.
Xavier Montagutelli +3 more
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