Results 21 to 30 of about 375,593 (258)

Genomic Diversity of CRESS DNA Viruses in the Eukaryotic Virome of Swine Feces

open access: yesMicroorganisms, 2021
Replication-associated protein (Rep)-encoding single-stranded DNA (CRESS DNA) viruses are a diverse group of viruses, and their persistence in the environment has been studied for over a decade.
Enikő Fehér   +5 more
doaj   +1 more source

Genetic Diversity and Characterization of Circular Replication (Rep)-Encoding Single-Stranded (CRESS) DNA Viruses

open access: yesMicrobiology Spectrum, 2022
The CRESS-DNA viruses are the ubiquitous virus detected in almost all eukaryotic life trees and play an essential role in the maintaining ecosystem of the globe. Still, their genetic diversity is not fully understood.
Perumal Arumugam Desingu, K. Nagarajan
doaj   +1 more source

The Evasion of Antiviral Innate Immunity by Chicken DNA Viruses

open access: yesFrontiers in Microbiology, 2021
The innate immune system constitutes the first line of host defense. Viruses have evolved multiple mechanisms to escape host immune surveillance, which has been explored extensively for human DNA viruses. There is growing evidence showing the interaction
Li Gao, Shijun Zheng, Yongqiang Wang
doaj   +1 more source

DNA virome of ticks in the Northeast and Hubei provinces of China reveals diverse single-stranded circular DNA viruses

open access: yesParasites & Vectors, 2023
Background Ticks are medically important vectors capable of transmitting a variety of pathogens to and between host species. Although the spectrum of tick-borne RNA viruses has been frequently investigated, the diversity of tick-borne DNA viruses remains
Yuhang Liu   +10 more
doaj   +1 more source

The main DNA viruses significantly affecting pig livestock

open access: yesJournal of Veterinary Research, 2020
Swine DNA viruses have developed unique mechanisms for evasion of the host immune system, infection and DNA replication, and finally, construction and release of new viral particles.
Díaz Carlos   +2 more
doaj   +1 more source

Contribution of hypoxia inducible factor-1 during viral infections

open access: yesVirulence, 2020
Hypoxia-inducible factor 1 (HIF-1) is a transcription factor that plays critical roles during the cellular response to hypoxia. Under normoxic conditions, its function is tightly regulated by the degradation of its alpha subunit (HIF-1α), which impairs ...
Antonia Reyes   +5 more
doaj   +1 more source

Responsiveness to basement membrane extract as a possible trait for tumorigenicity characterization

open access: yesVaccine: X, 2019
Immortalized cell lines used to produce vaccines are expected to be described in terms of their tumorigenicity. However, current in vivo tumorigenicity assays can be time-consuming and results can be equivocal, especially for weakly tumorigenic cells ...
Haruhiko Murata   +7 more
doaj   +1 more source

First Report on Detection and Complete Genomic Analysis of a Novel CRESS DNA Virus from Sea Turtles

open access: yesPathogens, 2023
To date, only a handful of viruses have been identified in sea turtles. Although eukaryotic circular Rep (replication initiation protein)-encoding single-stranded DNA (CRESS DNA) viruses have been reported from a wide variety of terrestrial species, and ...
Kerry Gainor   +8 more
doaj   +1 more source

Systematic CpT (ApG) depletion and CpG excess are unique genomic signatures of large DNA viruses infecting invertebrates. [PDF]

open access: yesPLoS ONE, 2014
Differences in the relative abundance of dinucleotides, if any may provide important clues on host-driven evolution of viruses. We studied dinucleotide frequencies of large DNA viruses infecting vertebrates (n = 105; viruses infecting mammals = 99 ...
Mohita Upadhyay   +2 more
doaj   +1 more source

Three-Dimensional Architecture of the Human BRCA1-A Histone Deubiquitinase Core Complex

open access: yesCell Reports, 2016
BRCA1 is a tumor suppressor found to be mutated in hereditary breast and ovarian cancer and plays key roles in the maintenance of genomic stability by homologous recombination repair.
Otto J.P. Kyrieleis   +9 more
doaj   +1 more source

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