Results 101 to 110 of about 7,455 (179)

Poxvirus Host Range Genes and Virus–Host Spectrum: A Critical Review

Viruses, 2017
The Poxviridae family is comprised of double-stranded DNA viruses belonging to nucleocytoplasmic large DNA viruses (NCLDV). Among the NCLDV, poxviruses exhibit the widest known host range, which is likely observed because this viral family has been more ...
Graziele Pereira Oliveira, Rodrigo Araújo Lima Rodrigues, Maurício Teixeira Lima, Betânia Paiva Drumond, Jônatas Santos Abrahão   +4 more
doaj   +1 more source

Alternative Splicing: Molecular Mechanisms, Biological Functions, Diseases, and Potential Therapeutic Targets

MedComm, Volume 6, Issue 12, December 2025.
Alternative splicing (AS) expands proteomic diversity and functional complexity in eukaryotes, regulated by spliceosomal components, RNA elements, and epigenetic modifications. Dysregulated AS contributes to diseases, including cancer, neurodegenerative disorders, and cardiovascular conditions, among others. Therapeutic interventions, such as antisense
Zhi‐Min Zhu, Xiao‐Mei Wu, Yan Hu, Xiao‐Lan Bian, Ya‐Qin Wang, Qiong‐Ni Zhu   +5 more
wiley   +1 more source

The genome of the brown alga Ectocarpus siliculosus contains a series of viral DNA pieces, suggesting an ancient association with large dsDNA viruses

BMC Evolutionary Biology, 2008
Background Ectocarpus siliculosus virus-1 (EsV-1) is a lysogenic dsDNA virus belonging to the super family of nucleocytoplasmic large DNA viruses (NCLDV) that infect Ectocarpus siliculosus, a marine filamentous brown alga. Previous studies indicated that
Boland Wilhelm, Delaroque Nicolas
doaj   +1 more source

The Primary Enveloped Virion of Herpes Simplex Virus 1: Its Role in Nuclear Egress [PDF]

, 2017
Many viruses migrate between different cellular compartments for successive stages of assembly. The HSV-1 capsid assembles in the nucleus and then transfers into the cytoplasm.
Cheng, N, Fontana, J, Heymann, JB, Newcomb, WW, Steven, AC, Winkler, DC   +5 more
core   +1 more source

Expression of alternatively spliced human T-cell leukemia virus type 1 mRNAs is influenced by mitosis and by a novel cis-acting regulatory sequence [PDF]

, 2016
Human T-cell leukemia virus type 1 (HTLV-1) expression depends on the concerted action of Tax, which drives transcription of the viral genome, and Rex, which favors expression of incompletely spliced mRNAs and determines a 2-phase temporal pattern of ...
Bona, Marion K., Cavallari, Ilaria, Ciminale, Vincenzo, D'Agostino, DONNA MIA, Franchini, Genoveffa, Legrice, Stuart F. J., Rende, Francesca, SILIC-BENUSSI, Micol, Sztuba Solinska, Joanna, Tognon, Martina   +9 more
core   +1 more source

A distinct lineage of giant viruses brings a rhodopsin photosystem to unicellular marine predators. [PDF]

, 2019
Giant viruses are remarkable for their large genomes, often rivaling those of small bacteria, and for having genes thought exclusive to cellular life.
Bachy, Charles, Choi, Chang Jae, DeLong, Edward F, Hehenberger, Elisabeth, Hosaka, Toshiaki, Irwin, Nicholas AT, Iwasaki, Wataru, Keeling, Patrick J, Kimura-Someya, Tomomi, Kojima, Keiichi, Kurihara, Rika, Leonard, Guy, Malmstrom, Rex R, Mende, Daniel R, Nakajima, Yu, Needham, David M, Olson, Daniel K, Poirier, Camille, Richards, Thomas A, Santoro, Alyson E, Shirouzu, Mikako, Sudek, Sebastian, Sudo, Yuki, Wilken, Susanne, Worden, Alexandra Z, Yoshizawa, Susumu, Yung, Cheuk-Man   +26 more
core   +5 more sources

Metagenomic Characterization of the Viral Community of the South Scotia Ridge

Viruses, 2019
Viruses are the most abundant biological entities in aquatic ecosystems and harbor an enormous amount of genetic diversity. Whereas their influence on marine ecosystems is widely acknowledged, current information about their diversity remains limited. We
Qingwei Yang, Chen Gao, Yong Jiang, Min Wang, Xinhao Zhou, Hongbing Shao, Zheng Gong, Andrew McMinn   +7 more
doaj   +1 more source

O-Linked glycosylation in Acanthamoeba polyphaga mimivirus [PDF]

, 2017
Acanthamoeba polyphaga mimivirus is a member of the giant nucleocytoplasmic large DNA viruses, infecting various Acanthamoeba spp. The genomes of giant viruses encode components previously thought to be exclusive to cellular life, such as proteins ...
Hennet, Thierry, Hülsmeier, Andreas J.
core  

Influenza A Virus Host Shutoff Disables Antiviral Stress-Induced Translation Arrest [PDF]

, 2014
Influenza A virus (IAV) polymerase complexes function in the nucleus of infected cells, generating mRNAs that bear 5′ caps and poly(A) tails, and which are exported to the cytoplasm and translated by host machinery.
Anderson, Paul, Emara, Mohamed M., Hatchette, Todd F., Johnston, Benjamin P., Khaperskyy, Denys A., McCormick, Craig   +5 more
core   +1 more source

Characterization of Medusavirus encoded histones reveals nucleosome-like structures and a unique linker histone

Nature Communications
The organization of DNA into nucleosomes is a ubiquitous and ancestral feature that was once thought to be exclusive to the eukaryotic domain of life. Intriguingly, several representatives of the Nucleocytoplasmic Large DNA Viruses (NCLDV) encode histone-
Chelsea M. Toner, Nicole M. Hoitsma, Sashi Weerawarana, Karolin Luger   +3 more
doaj   +1 more source