Versatile roles of disordered transcription factor effector domains in transcriptional regulation
Disordered effector domains (EDs) of transcription factors (TFs) play versatile roles in transcriptional regulation. These include mediating protein–protein interactions with protein complexes like, facilitating condensate formation to enhance transcriptional efficiency, modulating DNA‐binding specificity through genome scanning, and serving as hubs ...
Rhea R. Datta+3 more
wiley +1 more source
DDX18 coordinates nucleolus phase separation and nuclear organization to control the pluripotency of human embryonic stem cells. [PDF]
Shi X+19 more
europepmc +1 more source
Cytopathology, Volume 36, Issue 3, Page 278-280, May 2025.
Jaiden Townsend, Miguel Perez‐Machado
wiley +1 more source
Transcription‐coupled repair: tangled up in convoluted repair
In this review, we discuss recent findings derived from diverse genomic, biochemical and structural, imaging, and functional studies (B–E) that culminated in deep mechanistic insight (A) into the vital cellular process of transcription‐coupled nucleotide excision repair (TC‐NER).
Diana A. Llerena Schiffmacher+3 more
wiley +1 more source
USP39 phase separates into the nucleolus and drives lung adenocarcinoma progression by promoting GLI1 expression. [PDF]
Cheng S+13 more
europepmc +1 more source
ABSTRACT The smoothtail spiny lobster (Panulirus laevicauda) is one of the main target species for fisheries in Brazil. We aimed to estimate reproductive parameters of this species in support of a minimum legal size limit for the region. A sample of 508 individuals ranged 13.75–100 mm in cephalothorax length (CL) from the southern coast of Espírito ...
Andressa C. M. de Melo+5 more
wiley +1 more source
Decoding the Nucleolar Role in Meiotic Recombination and Cell Cycle Control: Insights into Cdc14 Function. [PDF]
Alonso-Ramos P, Carballo JA.
europepmc +1 more source
Case Report—Cytopathological Diagnosis of Metastatic Squamous Cell Carcinoma in Vitreous Fluid
Cytopathology, EarlyView.
Poorva Singh+3 more
wiley +1 more source
Pathological significance of intranuclear structures in liver biopsy samples
Schematic representation of the potential significance of three distinct nuclear structures. Glycogenated nuclei reflects excessive glycogen accumulation in the hepatocytes. Nucleoplasmic lipid droplets form in the nucleus during hepatocyte injury. Cytoplasmic lipid droplets in the nucleoplasmic reticulum are suppressed when there is excessive fat ...
Norihiro Imai+15 more
wiley +1 more source
A nuclear protein quality control system for elimination of nucleolus-related inclusions. [PDF]
Brunello L+11 more
europepmc +1 more source