Results 121 to 130 of about 72,696 (188)

Versatile roles of disordered transcription factor effector domains in transcriptional regulation

open access: yesThe FEBS Journal, EarlyView.
Disordered effector domains (EDs) of transcription factors (TFs) play versatile roles in transcriptional regulation. These include mediating protein–protein interactions with protein complexes like, facilitating condensate formation to enhance transcriptional efficiency, modulating DNA‐binding specificity through genome scanning, and serving as hubs ...
Rhea R. Datta   +3 more
wiley   +1 more source

DDX18 coordinates nucleolus phase separation and nuclear organization to control the pluripotency of human embryonic stem cells. [PDF]

open access: yesNat Commun
Shi X   +19 more
europepmc   +1 more source

Transcription‐coupled repair: tangled up in convoluted repair

open access: yesThe FEBS Journal, EarlyView.
In this review, we discuss recent findings derived from diverse genomic, biochemical and structural, imaging, and functional studies (B–E) that culminated in deep mechanistic insight (A) into the vital cellular process of transcription‐coupled nucleotide excision repair (TC‐NER).
Diana A. Llerena Schiffmacher   +3 more
wiley   +1 more source

USP39 phase separates into the nucleolus and drives lung adenocarcinoma progression by promoting GLI1 expression. [PDF]

open access: yesCell Commun Signal
Cheng S   +13 more
europepmc   +1 more source

Reproductive Biology of the Smoothtail Spiny Lobster (Panulirus laevicauda) to Support Fisheries Management in Southeastern Brazil

open access: yesFisheries Management and Ecology, EarlyView.
ABSTRACT The smoothtail spiny lobster (Panulirus laevicauda) is one of the main target species for fisheries in Brazil. We aimed to estimate reproductive parameters of this species in support of a minimum legal size limit for the region. A sample of 508 individuals ranged 13.75–100 mm in cephalothorax length (CL) from the southern coast of Espírito ...
Andressa C. M. de Melo   +5 more
wiley   +1 more source

Case Report—Cytopathological Diagnosis of Metastatic Squamous Cell Carcinoma in Vitreous Fluid

open access: yes
Cytopathology, EarlyView.
Poorva Singh   +3 more
wiley   +1 more source

Pathological significance of intranuclear structures in liver biopsy samples

open access: yesHepatology Research, EarlyView.
Schematic representation of the potential significance of three distinct nuclear structures. Glycogenated nuclei reflects excessive glycogen accumulation in the hepatocytes. Nucleoplasmic lipid droplets form in the nucleus during hepatocyte injury. Cytoplasmic lipid droplets in the nucleoplasmic reticulum are suppressed when there is excessive fat ...
Norihiro Imai   +15 more
wiley   +1 more source

A nuclear protein quality control system for elimination of nucleolus-related inclusions. [PDF]

open access: yesEMBO J
Brunello L   +11 more
europepmc   +1 more source

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