Results 91 to 100 of about 597,655 (179)

Predicting Regioselectivity in Nucleophilic Aromatic Substitution

, 2016
We have investigated practical and computationally efficient methods for the quantitative prediction of regioisomer distribution in kinetically controlled nucleophilic aromatic substitution reactions.
Simone Tomasi (139458), Björn Herschend (2095801), Mats Svensson (1822822), Magnus Liljenberg (2095804), Tore Brinck (1417816), Tobias Rein (1353243)   +5 more
core   +1 more source

High-Yield Synthesis of N⁴-(3-Chloro-4-fluorophenyl)-7-((4-methoxybenzyl)thio)quinazoline-4,6-diamine via N-(3-Chloro-4-fluorophenyl)-7-((4-methoxybenzyl)thio)-6-nitroquinazolin-4-amine

Molbank
The target compound, N4-(3-chloro-4-fluorophenyl)-7-((4-methoxybenzyl)thio)quinazoline-4,6-diamine, was synthesized in two steps from N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine by a nucleophilic aromatic substitution, yielding N-(3 ...
Susila Thapa, Jeanne L. Bolliger
doaj   +1 more source

Nucleophilic Aromatic Substitution (S_NAr) and Related Reactions of Porphyrinoids: Mechanistic and Regiochemical Aspects. [PDF]

European J Org Chem, 2021
Sample HC, Senge MO.
europepmc   +1 more source

Continuous Flow Nucleophilic Aromatic Substitution with Dimethylamine Generated in Situ by Decomposition of DMF

, 2013
A safe, practical, and scalable continuous flow protocol for the in situ generation of dimethylamine from DMF followed by nucleophilic aromatic substitution of a broad range of aromatic and heteroaromatic halides is ...
Anders Foller Larsen, Ritzén, Andreas, Trine P. Petersen, Larsen, Anders Foller, Trond Ulven, Petersen, Trine P, Andreas Ritzén, Ulven, Trond   +7 more
core   +1 more source

A broadly applicable quantitative relative reactivity model for nucleophilic aromatic substitution (S_NAr) using simple descriptors. [PDF]

Chem Sci, 2022
Lu J, Paci I, Leitch DC.
europepmc   +1 more source

Fluorescent probes based on nucleophilic aromatic substitution reactions for reactive sulfur and selenium species: Recent progress, applications, and design strategies. [PDF]

Coord Chem Rev, 2021
Liu Y, Yu Y, Zhao Q, Tang C, Zhang H, Qin Y, Feng X, Zhang J.   +7 more
europepmc   +1 more source

Synthesis of 1H-quinazoline-4-ones using intramolecular aromatic nucleophilic substitution

ARKIVOC, 2003
W. Russell Bowman, Harry Heaney, Philip H. G. Smith   +2 more
doaj   +1 more source

Photochemical aromatic substitution

, 2003
The photochemical aromatic substitution reactions described within this article are mainly devoted to homocyclic aromatic compounds. The work described is focused on the mechanism of the various reactions described.
Karapire C., Icli S.
core  

Nucleophilic Aromatic Substitution with Ethylenediamine. [PDF]

Acta Chemica Scandinavica, 1965
Bo Lamm, Finn Christenssen, Nils Jakob Gröndahl, Charles Guthrie, Merv Hinton   +4 more
openaire   +1 more source

High-Throughput Experimentation and Continuous Flow Evaluation of Nucleophilic Aromatic Substitution Reactions. [PDF]

ACS Comb Sci, 2020
Jaman Z, Logsdon DL, Szilágyi B, Sobreira TJP, Aremu D, Avramova L, Cooks RG, Thompson DH.   +7 more
europepmc   +1 more source