Results 1 to 10 of about 21,712 (116)

Transetherification of 2,4-dimethoxynitrobenzene by aromatic nucleophilic substitution. [PDF]

open access: yesPLoS ONE, 2017
In view of the few reports concerning aromatic nucleophilic substitution reactions featuring an alkoxy group as a leaving group, the aromatic nucleophilic substitution of 2,4-dimethoxynitrobenzene was investigated with a bulky t-butoxide nucleophile ...
Jiho Song   +7 more
doaj   +2 more sources

Tuning Covalent Organic Frameworks via Nucleophilic Aromatic Substitution [PDF]

open access: yesSmall Science
A family of covalent organic frameworks (COFs) with tuned properties has been prepared through nucleophilic aromatic substitution (SNAr) from a fluorinated imine‐linked COF (COF‐F).
Óscar González‐Rosell   +8 more
doaj   +2 more sources

Nucleophilic Aromatic Substitution of Polyfluoroarene to Access Highly Functionalized 10-Phenylphenothiazine Derivatives

open access: yesMolecules, 2021
Nucleophilic aromatic substitution (SNAr) reactions can provide metal-free access to synthesize monosubstituted aromatic compounds. We developed efficient SNAr conditions for p-selective substitution of polyfluoroarenes with phenothiazine in the presence
Toshifumi Dohi, Kotaro Kikushima
exaly   +3 more sources

A Greener and Efficient Method for Nucleophilic Aromatic Substitution of Nitrogen-Containing Fused Heterocycles

open access: yesMolecules, 2018
A simple and efficient methodology for the nucleophilic aromatic substitution of nitrogen-containing fused heterocycles with interesting biological activities has been developed in an environmentally sound manner using polyethylene glycol (PEG-400) as ...
Mohammed Loubidi   +2 more
exaly   +3 more sources

Synthesis of 4-[(1H-Benzimidazol-2-yl)sulfanyl]benzaldehyde and 2-({4-[(1H-Benzimidazol-2-yl)sulfanyl]phenyl}methylidene)hydrazine-1-carbothioamide

open access: yesMolbank, 2021
Here we describe the preparation of 2-(4-((1H-benzo[d]imidazol-2-yl)thio)-benzylidene)-hydrazine-1-carbothioamide in two steps. In the first step, 1,3-dihydro-2H-1,3-benzimidazole-2-thione was reacted with 4-fluorobenzaldehyde in DMSO to get 4-[(1H ...
Mustafa Turki Ubeid   +2 more
doaj   +1 more source

Microwave-assisted synthesis of azepines via nucleophilic aromatic substitution [PDF]

open access: yesJournal of the Serbian Chemical Society, 2016
A novel and efficient route has been developed to afford 5H-dipyridoazepine derivatives from primary amines and 3,3'-(Z)-ethene-1,2-di-ylbis(4-chloropyridine).
Božinović Nina   +2 more
doaj   +1 more source

Perfluoropyridine: Discovery, Chemistry, and Applications in Polymers and Material Science

open access: yesMolecules, 2022
Perfluoropyridine (PFPy) is an organofluorine compound that has been employed for a variety of applications, from straightforward chemical synthesis to more advanced functions, such as fluorinated networks and polymers. This can be directly attributed to
Ritesh Gautam   +4 more
doaj   +1 more source

New opportunities for the synthesis of quinoxaline derivatives

open access: yesChimica Techno Acta, 2019
Convenient methods for the synthesis of quinoxaline derivatives with the use of nucleophilic aromatic substitution of hydrogen in heteroaromatic part of molecule in conditions of the acid catalysis were elaborated.
Olga S. Koptyaeva   +4 more
doaj   +1 more source

1-(2,5-Dimethoxy-4-nitrophenyl)piperidine

open access: yesMolbank, 2023
Treatment of the non-purified mixture of dinitro isomers obtained from the nitration of 1,4-dimethoxybenzene with piperidine led to the isolation of novel but minor adduct, 1-(2,5-dimethoxy-4-nitrophenyl)piperidine (2b) in 15% yield.
Tanjia M. Syeda   +4 more
doaj   +1 more source

Mechanisms of Nucleophilic Aromatic and Hetero-aromatic Substitution. Recent Developments

open access: yesCHIMIA, 1980
There are now at least five well defined mechanisms of nucleophilic aromatic and heteroaromatic substitution. Three of them, the SNAr, the benzyne and the SN1 mechanism, have been known for a long time, whereas the SRN1and the SN (ANRORC) mechanisms are
Claude F. Bernasconi
doaj   +1 more source

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