Results 21 to 30 of about 597,754 (265)
Molecules, 2023 Quinolone and quinoline derivatives are frequently found as substructures in pharmaceutically active compounds. In this paper, we describe a procedure for the synthesis of azuleno[2,1-b]quinolones and quinolines from 2-arylaminoazulene derivatives, which
Taku Shoji +6 more
doaj +1 more source
Synthesis and nucleophilic aromatic substitution of 3-fluoro-5-nitro-1-(pentafluorosulfanyl)benzene
Beilstein Journal of Organic Chemistry, 2016 3-Fluoro-5-nitro-1-(pentafluorosulfanyl)benzene was prepared by three different ways: as a byproduct of direct fluorination of 1,2-bis(3-nitrophenyl)disulfane, by direct fluorination of 4-nitro-1-(pentafluorosulfanyl)benzene, and by fluorodenitration of ...
Javier Ajenjo +3 more
doaj +1 more source
Unravelling nucleophilic aromatic substitution pathways with bimetallic nucleophiles [PDF]
Chemical Communications, 2019 Reaction of nucleophiles containing polar (Fe–Mg) and apolar (Mg–Mg) bonds with 2-(pentafluorophenyl)pyridine are calculated to proceed by stepwise and concerted S N Ar pathways respectively.
Martí Garçon +3 more
openaire +4 more sources
Molecules, 2005 An efficient protocol for the amination of 6-chloropurine derivatives through nucleophilic aromatic substitution under microwave irradiation was developed and applied to the synthesis in two steps of a series of new acyclic nucleosides (acyclovir ...
H.-G. Schmalz, A. Lanver
doaj +1 more source
Cation Radical Accelerated Nucleophilic Aromatic Substitution via Organic Photoredox Catalysis [PDF]
, 2017 Nucleophilic aromatic substitution (SNAr) is a direct method for arene functionalization; however, it can be hampered by low reactivity of arene substrates and their availability.
Tay, Nicholas E. S., Nicewicz, David A.
core +1 more source
, 2021 Arylthiophene derivatives are potential components of functional materials, including organic electronics. Herein, we describe a nucleophilic aromatic substitution reaction of polyfluoroarenes using silylthiophenes as nucleophiles in the presence of a ...
Yoneda, Yuna +6 more
core +1 more source
Allylic cross-coupling using aromatic aldehydes as α-alkoxyalkyl anions
Beilstein Journal of Organic Chemistry, 2020 The allylic cross-coupling using aromatic aldehydes as α-alkoxyalkyl anions is described. The synergistic palladium/copper-catalyzed reaction of aromatic aldehydes, allylic carbonates, and a silylboronate produces the corresponding homoallylic alcohol ...
Akihiro Yuasa +2 more
doaj +1 more source
Molecules, 2006 The nitro group of methyl 3-nitropyridine-4-carboxylate (1) has successfully been replaced by fluoride anion via nucleophilic aromatic substitution to give the 3-fluoro- pyridine-4-carboxylate 2.
Anne Fiksdahl, Freddy Tjosaas
doaj +1 more source
Molecules, 2020 In this study, we present a complete description of the addition of a model nucleophile to the nitroaromatic ring in positions occupied either by hydrogen (the first step of the SNAr-H reaction) or a leaving group (SNAr-X reaction) using theoretical ...
Kacper Błaziak +2 more
doaj +1 more source
Frontiers in Chemistry, 2018 Nucleophilic aromatic substitution reactions of 4-chloroquinazoline toward aniline and hydrazine were used as a model system to experimentally show that a substrate bearing heteroatoms on the aromatic ring as substituent is able to establish ...
Bruno Sánchez +4 more
doaj +1 more source