Nucleophilic Aromatic Substitution of Polyfluoroarene to Access Highly Functionalized 10-Phenylphenothiazine Derivatives [PDF]
Molecules, 2021 Nucleophilic aromatic substitution (SNAr) reactions can provide metal-free access to synthesize monosubstituted aromatic compounds. We developed efficient SNAr conditions for p-selective substitution of polyfluoroarenes with phenothiazine in the presence
Kotaro Kikushima +3 more
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A Greener and Efficient Method for Nucleophilic Aromatic Substitution of Nitrogen-Containing Fused Heterocycles [PDF]
Molecules, 2018 A simple and efficient methodology for the nucleophilic aromatic substitution of nitrogen-containing fused heterocycles with interesting biological activities has been developed in an environmentally sound manner using polyethylene glycol (PEG-400) as ...
Joana F. Campos +3 more
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Concerted Nucleophilic Aromatic Substitution Reactions [PDF]
Angewandte Chemie - International Edition, 2019 AbstractRecent developments in experimental and computational chemistry have identified a rapidly growing class of nucleophilic aromatic substitutions that proceed by concerted (cSNAr) rather than classical, two‐step, SNAr mechanisms. Whereas traditional SNAr reactions require substantial activation of the aromatic ring by electron‐withdrawing ...
Darren L Poole +2 more
exaly +8 more sources
Tuning Covalent Organic Frameworks via Nucleophilic Aromatic Substitution [PDF]
Small ScienceA family of covalent organic frameworks (COFs) with tuned properties has been prepared through nucleophilic aromatic substitution (SNAr) from a fluorinated imine‐linked COF (COF‐F).
Óscar González‐Rosell +8 more
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Iterative Exponential Growth of Oxygen-Linked Aromatic Polymers Driven by Nucleophilic Aromatic Substitution Reactions [PDF]
Frontiers in Chemistry, 2021 This work presents the first transition metal-free synthesis of oxygen-linked aromatic polymers by integrating iterative exponential polymer growth (IEG) with nucleophilic aromatic substitution (SNAr) reactions.
Tyler J. Jaynes +10 more
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Synthesis and nucleophilic aromatic substitution of 3-fluoro-5-nitro-1-(pentafluorosulfanyl)benzene [PDF]
Beilstein Journal of Organic Chemistry, 2016 3-Fluoro-5-nitro-1-(pentafluorosulfanyl)benzene was prepared by three different ways: as a byproduct of direct fluorination of 1,2-bis(3-nitrophenyl)disulfane, by direct fluorination of 4-nitro-1-(pentafluorosulfanyl)benzene, and by fluorodenitration of ...
Javier Ajenjo +3 more
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Molecules, 2006 The nitro group of methyl 3-nitropyridine-4-carboxylate (1) has successfully been replaced by fluoride anion via nucleophilic aromatic substitution to give the 3-fluoro- pyridine-4-carboxylate 2.
Anne Fiksdahl, Freddy Tjosaas
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A new platform for the synthesis of diketopyrrolopyrrole derivatives via nucleophilic aromatic substitution reactions [PDF]
Beilstein Journal of Organic ChemistryDiketopyrrolopyrroles (DPPs) are a versatile group of dyes and pigments with valuable optoelectronic properties. In this work we report the synthesis of highly fluorescent DPP derivatives through straightforward nucleophilic aromatic substitution ...
Vitor A. S. Almodovar, Augusto C. Tomé
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Transetherification of 2,4-dimethoxynitrobenzene by aromatic nucleophilic substitution. [PDF]
PLoS ONE, 2017 In view of the few reports concerning aromatic nucleophilic substitution reactions featuring an alkoxy group as a leaving group, the aromatic nucleophilic substitution of 2,4-dimethoxynitrobenzene was investigated with a bulky t-butoxide nucleophile ...
Jiho Song +7 more
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Molbank, 2021 Here we describe the preparation of 2-(4-((1H-benzo[d]imidazol-2-yl)thio)-benzylidene)-hydrazine-1-carbothioamide in two steps. In the first step, 1,3-dihydro-2H-1,3-benzimidazole-2-thione was reacted with 4-fluorobenzaldehyde in DMSO to get 4-[(1H ...
Mustafa Turki Ubeid +2 more
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