Results 21 to 30 of about 597,655 (179)

Perfluoropyridine: Discovery, Chemistry, and Applications in Polymers and Material Science

Molecules, 2022
Perfluoropyridine (PFPy) is an organofluorine compound that has been employed for a variety of applications, from straightforward chemical synthesis to more advanced functions, such as fluorinated networks and polymers. This can be directly attributed to
Ritesh Gautam, Ian Geniza, Scott T. Iacono, Chadron M. Friesen, Abby R. Jennings   +4 more
doaj   +1 more source

A generally applicable quantitative reactivity model for nucleophilic aromatic substitution built from simple descriptors [PDF]

, 2022
We report a multivariate linear regression model able to make accurate predictions for the rate and regioselectivity of nucleophilic aromatic substitution (SNAr) reactions based on the electrophile structure.
Jingru, Lu, Irina, Paci, David, Leitch
core   +2 more sources

New opportunities for the synthesis of quinoxaline derivatives

Chimica Techno Acta, 2019
Convenient methods for the synthesis of quinoxaline derivatives with the use of nucleophilic aromatic substitution of hydrogen in heteroaromatic part of molecule in conditions of the acid catalysis were elaborated.
Olga S. Koptyaeva, Yuriy A. Azev, Yuriy M. Shafran, Tatyana A. Pospelova, Oleg N. Chupakhin   +4 more
doaj   +1 more source

1-(2,5-Dimethoxy-4-nitrophenyl)piperidine

Molbank, 2023
Treatment of the non-purified mixture of dinitro isomers obtained from the nitration of 1,4-dimethoxybenzene with piperidine led to the isolation of novel but minor adduct, 1-(2,5-dimethoxy-4-nitrophenyl)piperidine (2b) in 15% yield.
Tanjia M. Syeda, Muadh R. Al-Shaidi, Ibtihal Basri, Mahboub Merzouk, Fawaz Aldabbagh   +4 more
doaj   +1 more source

Transition-Metal-Mediated Nucleophilic Aromatic Substitution with Acids [PDF]

, 2016
Transition-metal-mediated nucleophilic aromatic substitution (S_NAr) reactions prefer that a suitably strong nucleophile be in an aprotic medium. Usually, using protic nucleophile/medium requires high reaction temperatures (>180 °C) to overcome the ...
Nielsen, Robert J., Johnson, Samantha I., O’Reilly, Matthew E., Gunnoe, T. Brent, Goddard, William A., III   +4 more
core   +2 more sources

Mechanisms of Nucleophilic Aromatic and Hetero-aromatic Substitution. Recent Developments

CHIMIA, 1980
There are now at least five well defined mechanisms of nucleophilic aromatic and heteroaromatic substitution. Three of them, the SNAr, the benzyne and the SN1 mechanism, have been known for a long time, whereas the SRN1and the SN (ANRORC) mechanisms are
Claude F. Bernasconi
doaj   +1 more source

Preparação de N-alquil derivados do 1-bromo-2,4-dinitrobenzeno e do 1-cloro-2-nitrobenzeno: Uma alternativa às aulas práticas de substituição nucleofílica aromática Preparation of N-alkyl derivatives of 1-bromo-2,4-dinitrobenzene and 1-chloro-2-nitrobenzene: An alternative to nucleophilic aromatic substitution practices

Química Nova, 2008
Preparation of the title compounds are described as an alternative nucleophilic aromatic substitution for practices in the graduate laboratory. The low toxicity and disponibility of the reagents make a suitable procedure approach to experiments regarding
Ayres Guimarães Dias, Felipe Martins Alves Pereira, Renato de Oliveira Soares   +2 more
doaj   +1 more source

Synthesis of Azuleno[2,1-b]quinolones and Quinolines via Brønsted Acid-Catalyzed Cyclization of 2-Arylaminoazulenes

Molecules, 2023
Quinolone and quinoline derivatives are frequently found as substructures in pharmaceutically active compounds. In this paper, we describe a procedure for the synthesis of azuleno[2,1-b]quinolones and quinolines from 2-arylaminoazulene derivatives, which
Taku Shoji, Mutsumi Takeuchi, Mayumi Uda, Yukino Ariga, Akari Yamazaki, Ryuta Sekiguchi, Shunji Ito   +6 more
doaj   +1 more source

Unravelling nucleophilic aromatic substitution pathways with bimetallic nucleophiles [PDF]

Chemical Communications, 2019
Reaction of nucleophiles containing polar (Fe–Mg) and apolar (Mg–Mg) bonds with 2-(pentafluorophenyl)pyridine are calculated to proceed by stepwise and concerted S N Ar pathways respectively.
Martí Garçon, Clare Bakewell, Andrew J. P. White, Mark R. Crimmin   +3 more
openaire   +4 more sources

Microwave-Assisted Amination of a Chloropurine Derivative in the Synthesis of Acyclic Nucleoside Analogues

Molecules, 2005
An efficient protocol for the amination of 6-chloropurine derivatives through nucleophilic aromatic substitution under microwave irradiation was developed and applied to the synthesis in two steps of a series of new acyclic nucleosides (acyclovir ...
H.-G. Schmalz, A. Lanver
doaj   +1 more source