Results 291 to 300 of about 286,275 (354)

Nucleoside reverse transcriptase inhibitors are anti-inflammatory and inhibit poly I:C-induced retinal pigment epithelium degeneration

, 2016
Shin‐ichi Fukuda, Junichi Fukuhara, Younghee Kim, Benjamin J. Fowler, Tetsuhiro Yasuma, Reo Yasuma, Takako Fukuhara, Nagaraj Kerur, Bradley D. Gelfand, Jayakrishna Ambati   +9 more
openalex   +1 more source

Electromechanical modelling and simulation of human‐induced pluripotent stem cell‐derived cardiomyocytes predict drug‐induced contractility effects

The Journal of Physiology, EarlyView.
Abstract figure legend A study described in this paper describes a new tool for hiPSC‐CM electromechanical behaviour simulations using mathematical modelling. The model enables in silico assays making drug testing quick, comprehensive and accurate. New hiPSC‐CM models can be used as a platform to integrate in vitro and in silico findings.
Milda Folkmanaite, Xin Zhou, Andreas Koschinski, Wan‐Hua Hong, Marilù Casini, Manuel Koch, Ursula Ravens, Remi Peyronnet, Manuela Zaccolo, Blanca Rodriguez   +9 more
wiley   +1 more source

HIV-1 drug resistance and associated risk factors in patients with antiretroviral therapy failure in Chongqing, China, 2019-2023. [PDF]

PLoS One
Zhang H, Wu P, Ye W.
europepmc   +1 more source

An efficient transition metal-free indolylation on 6-chloropurine ribonucleosides and photophysical studies of conjugated nucleosides. [PDF]

RSC Adv
Mondal SK, Singh S, Pal S.
europepmc   +1 more source

Enzymatic synthesis of key RNA therapeutic building blocks using simple phosphate donors. [PDF]

Nat Commun
Meng Q, Benckendorff C, Morrill C, Zhuo Y, Egerström A, Ní Cheallaigh A, Derrington SR, Obexer R, Ortmayer M, Levy CW, Finnigan JD, Charnock SJ, Turner NJ, Miller GJ, Lovelock SL.   +14 more
europepmc   +1 more source

Mechanisms Underlying Cedazuridine-Mediated Enhancement of Oral Decitabine Bioavailability. [PDF]

Cancer Res Commun
Anabtawi N, Drabison T, Ham AF, Boeckman M, Stromatt JC, Orwick SJ, Buelow DR, Kaur T, Ahmed EA, Eisenmann ED, Govindarajan R, Sparreboom A, Baker SD.   +12 more
europepmc   +1 more source

Familial SLC29A3-related histiocytosis with presumed choroidal infiltration: expanding the spectrum of histiocytosis-lymphadenopathy plus syndrome. [PDF]

Am J Ophthalmol Case Rep
Boulu X, Morin G, Attencourt C, Schmidt J, Tran THC.   +4 more
europepmc   +1 more source

Improved Nucleoside (2'-Deoxy)Ribosyltransferases Maximize Enzyme Promiscuity while Maintaining Catalytic Efficiency. [PDF]

ACS Chem Biol
Tang P, Zickuhr GM, Dickson AL, Harding CJ, Devi S, Lebl T, Harrison DJ, da Silva RG, Czekster CM.   +8 more
europepmc   +1 more source