Results 221 to 230 of about 127,063 (412)

Parametrised functor calculus: excision, spheres, and semiadditivity [PDF]

arXiv
We lay down the foundations of a theory of parametrised functor calculus, generalising parts of the functor calculus of Goodwillie. We introduce the notion of excisable posets and develop a theory of excisive approximations in this context. As an application, we introduce two different excisable posets when parametrising over an atomic orbital category.
arxiv  

ASH1L-MRG15 methyltransferase deposits H3K4me3 and FACT for damage verification in nucleotide excision repair. [PDF]

Nat Commun, 2023
Maritz C, Khaleghi R, Yancoskie MN, Diethelm S, Brülisauer S, Ferreira NS, Jiang Y, Sturla SJ, Naegeli H.   +8 more
europepmc   +1 more source

Conserved Residues of Human XPG Protein Important for Nuclease Activity and Function in Nucleotide Excision Repair [PDF]

, 1999
Angelos Constantinou, Daniela Gunz, Elizabeth L. Evans, Philippe Lalle, Paul A. Bates, Richard D. Wood, Stuart G. Clarkson   +6 more
openalex   +1 more source

Sperm‐Derived CircRNA‐1572 Regulates Embryogenesis and Zygotic Genome Activation by Targeting CCNB2 via Bta‐miR‐2478‐L‐2

Advanced Science, EarlyView.
Sperm‐derived circRNA‐1572 competitively binds to bta‐miR‐2478‐L‐2 through a “sponge” mechanism to regulate cyclin B2 (CCNB2) expression, thereby modulating the distribution of fibrous actin (F‐actin) in early pig embryos, ensuring proper chromosome segregation during mitosis, and facilitating normal embryo cleavage and zygotic genome activation.
Yanfang Wu, Yaochang Wei, Yuelin Li, Yiming Dou, YongQiang Yang, Hanghang Liu, Xiaoyan Wang, Zheng Wang, Jianmin Su, Yong Zhang, Yongsheng Wang   +10 more
wiley   +1 more source

Genome-wide analysis of transcription-coupled repair reveals novel transcription events in Caenorhabditis elegans.

PLoS Genetics
Bulky DNA adducts such as those induced by ultraviolet light are removed from the genomes of multicellular organisms by nucleotide excision repair, which occurs through two distinct mechanisms, global repair, requiring the DNA damage recognition-factor ...
Cansu Kose, Laura A Lindsey-Boltz, Aziz Sancar, Yuchao Jiang   +3 more
doaj   +1 more source

Involvement of Nucleotide Excision Repair and Rec-Dependent Pathway Genes for UV Radiation Resistance in Deinococcus irradiatisoli 17bor-2. [PDF]

Genes (Basel), 2023
Subramani G, Srinivasan S.
europepmc   +1 more source

Transcription-induced Cleavage of Immunoglobulin Switch Regions by Nucleotide Excision Repair Nucleases in Vitro [PDF]

, 2000
Ming Tian, Frederick W. Alt
openalex   +1 more source

Assessment and Mitigation of CRISPR‐Cas9‐Induced Nontargeted Translocations

Advanced Science, EarlyView.
Various inverted repeat elements are dispersed throughout genomes. This study reveals that these elements can cause significant chromosomal rearrangements when CRISPR editing occurs in their proximity. The risk can be mitigated by incorporating inverted repeat‐homologous segments into the CRISPR system, which represents a promising strategy for ...
Zhiyang Hou, Qiyi Yi, Mengying Wu, Lijun Wu, Fanghua Li, Ting Wang, Po Bian   +6 more
wiley   +1 more source

Repair of UV damage in plants by nucleotide excision repair: Arabidopsis UVH1 DNA repair gene is a homolog of Saccharomyces cerevisiae Rad1 [PDF]

, 2000
Zongrang Liu, Gazi S. Hossain, María A. Islas‐Osuna, David L. Mitchell, David W. Mount   +4 more
openalex   +1 more source

Targeting miRNA‐1a and miRNA‐15b: A Novel Combinatorial Strategy to Drive Adult Cardiac Regeneration

Advanced Science, EarlyView.
The article explores a novel therapeutic strategy for cardiac regeneration by targeting miRNA‐1a and miRNA‐15b. Combinatorial inhibition of miR‐1a and miR‐15b enhances cardiomyocyte proliferation, improves heart function, and reduces fibrosis in myocardial infarction models.
Ting Yuan, Meiqian Wu, Chaonan Zhu, Hao Yu, Minh Duc Pham, Katharina Bottermann, Yijie Mao, Yue Wang, Mathias Langner, Mirko Peitzsch, Arka Provo Das, Silke Kauferstein, Jonathan Ward, Peter Mirtschink, Andreas Michael Zeiher, Stefanie Dimmeler, Jaya Krishnan   +16 more
wiley   +1 more source