Results 221 to 230 of about 82,343 (351)

piR‐RCC Suppresses Renal Cell Carcinoma Progression by Facilitating YBX‐1 Cytoplasm Localization

Advanced Science, EarlyView.
PIWI‐interacting RNAs (piRNAs), a novel category of small non‐coding RNAs, have been implicated in the development of various diseases. This study explores the tumor‐suppressive mechanism of a downregulated piRNA (designated piR‐RCC) in renal cell carcinoma (RCC), and provides a delivery strategy targeting RCC tumor by constructing a cell membrane ...
Ruyue Wang, Fan Li, Yudong Lin, Zeyi Lu, Wenqin Luo, Zhehao Xu, Ziwei Zhu, Yi Lu, Xudong Mao, Yang Li, Zhinian Shen, Haohua Lu, Yining Chen, Liqun Xia, Mingchao Wang, Lifeng Ding, Gonghui Li   +16 more
wiley   +1 more source

Clinical and molecular overlap between nucleotide excision repair (NER) disorders and <i>DYRK1A</i> haploinsufficiency syndrome. [PDF]

Front Neurosci
Le May N, Courraud J, Boujelbène I, Obringer C, Ogi T, Lehmann AR, Laffargue F, Lehalle D, Mizuno S, Mohammed S, Ormières C, Willems M, Laugel V, Calmels N.   +13 more
europepmc   +1 more source

A genome-wide screen reveals that Dyrk1A kinase promotes nucleotide excision repair by preventing aberrant overexpression of cyclin D1 and p21. [PDF]

J Biol Chem, 2023
Bélanger F, Roussel C, Sawchyn C, St-Hilaire E, Gezzar-Dandashi S, Kimenyi Ishimwe AB, Mallette FA, Wurtele H, Drobetsky E.   +8 more
europepmc   +1 more source

Involvement of Nucleotide Excision Repair in a Recombination-Independent and Error-Prone Pathway of DNA Interstrand Cross-Link Repair [PDF]

, 2001
Xin Wang, Carolyn A. Peterson, Huyong Zheng, Rodney S. Nairn, Randy J. Legerski, Lei Li   +5 more
openalex   +1 more source

De Novo Reconstruction of 3D Human Facial Images from DNA Sequence

Advanced Science, EarlyView.
This study introduces Difface, a novel deep‐learning model for reconstructing 3D facial images only from DNA data. By integrating transformer networks, spiral convolutions, and a diffusion model, Difface directly aligns high‐dimensional SNP data with 3D facial structures.
Mingqi Jiao, Jiarui Li, Bingxu Zhong, Siyuan Du, Shuning Li, Manfei Zhang, Qibin Zhang, Zhongming Liang, Fan Liu, Chunman Zuo, Sijia Wang, Luonan Chen   +11 more
wiley   +1 more source

Nucleotide Excision Repair: Insights into Canonical and Emerging Functions of the Transcription/DNA Repair Factor TFIIH. [PDF]

Genes (Basel)
Zachayus A, Loup-Forest J, Cura V, Poterszman A.   +3 more
europepmc   +1 more source

A scanning-to-incision switch in TFIIH-XPG induced by DNA damage licenses nucleotide excision repair. [PDF]

Nucleic Acids Res, 2023
Bralić A, Tehseen M, Sobhy MA, Tsai CL, Alhudhali L, Yi G, Yu J, Yan C, Ivanov I, Tsutakawa SE, Tainer JA, Hamdan SM.   +11 more
europepmc   +1 more source

A multistep damage recognition mechanism for global genomic nucleotide excision repair [PDF]

, 2001
Kaoru Sugasawa, Tomoko Okamoto, Yuichiro Shimizu, Chikahide Masutani, Shigenori Iwai, Fumio Hanaoka   +5 more
openalex   +1 more source

Chronic Psychological Stress Induces Cardiomyocyte Hypertrophy Through Corticosterone‐Glucocorticoid Receptor‐LAMA5 Axis

Advanced Science, EarlyView.
In vivo experiments suggest that cardiomyocyte hypertrophy is an early manifestation of cardiac pathological changes induced by chronic psychological stress. In vivo and in vitro experiments suggest that the corticosterone‐glucocorticoid receptor‐LAMA5 axis mediates cardiomyocyte hypertrophy induced by chronic psychological stress. The clinical results
Chuanjing Zhang, Yongfei Song, Xiaojun Jin, Qingbo Xu, Honghua Ye, Zhuonan Wu, Hui Lin, Jiale Hu, Chen Huang, Jianqing Zhou, Jiangfang Lian   +10 more
wiley   +1 more source

Does the XPA-FEN1 Interaction Concern to Nucleotide Excision Repair or Beyond? [PDF]

Biomolecules
Krasikova YS, Maltseva EA, Khodyreva SN, Evdokimov AN, Rechkunova NI, Lavrik OI.   +5 more
europepmc   +1 more source