Results 251 to 260 of about 82,343 (351)

Conformation, Recognition by High Mobility Group Domain Proteins, and Nucleotide Excision Repair of DNA Intrastrand Cross-links of Novel Antitumor Trinuclear Platinum Complex BBR3464 [PDF]

, 2001
Jana Zehnulová, Jana Kašpárková, Nicholas P. Farrell, Viktor Brabec   +3 more
openalex   +1 more source

The DEC2‐SCN2A Axis is Essential for the Anticonvulsant Effects of Cannabidiol by Modulating Neuronal Plasticity

Advanced Science, EarlyView.
This study identifies DEC2 as a critical transcriptional repressor of Scn2a that directly binds E‐box motifs in its promoter to regulate neuronal plasticity and epileptogenesis. Functional manipulation of DEC2 alters seizure susceptibility in vivo. Cannabidiol enhances this repression, unveiling a novel DEC2‐SCN2A axis underlying its anticonvulsant ...
Huifang Song, Yifan Wang, Lili Wang, Chang Guo, Shiqi Liu, Yi Rong, Jiawen Tian, Chao Peng, Yuying Shao, Zhixiong Ma, Na Li, Jingliang Zhang, Zijun Peng, Xu Yan, Hangwei Fa, Xinyue Ma, Jie Dong, Jinping Ji, Chen Yang, Haocheng Chen, Jing Liang, Qi Sun, Yang Yang, Weining Ma, Zhuo Huang   +24 more
wiley   +1 more source

Correction to 'CARM1/PRMT4 facilitates XPF-ERCC1 heterodimer assembly and maintains nucleotide excision repair activity'. [PDF]

Nucleic Acids Res
europepmc   +1 more source

In vivo nucleotide excision repair by mycobacterial UvrD1 requires ATP hydrolysis but does not depend on cysteine disulfide-mediated dimerization and DNA unwinding. [PDF]

Nucleic Acids Res
Warren GM, Shuman S.
europepmc   +1 more source

The 26S proteasome negatively regulates the level of overall genomic nucleotide excision repair

, 2000
Lori Lommel
openalex   +1 more source

Nucleotide excision repair in rat male germ cells: low level of repair in intact cells contrasts with high dual incision activity in vitro [PDF]

, 2001
Jacob G. Jansen, Ann‐Karin Olsen, Richard Wiger, Hanspeter Naegeli, P. de Boer, F. van der Hoeven, Jørn A. Holme, Gunnar Brunborg, Leon H.F. Mullenders   +8 more
openalex   +1 more source

Enhancing Specificity, Precision, Accessibility, Flexibility, and Safety to Overcome Traditional CRISPR/Cas Editing Challenges and Shape Future Innovations

Advanced Science, EarlyView.
CRISPR/Cas9, while transformative, faces challenges in specificity, precision, delivery, accessibility, flexibility, and safety. This review addresses these limitations by highlighting strategies to reduce off‐target effects, exploring HDR‐based and alternative editing approaches, and evaluating advanced delivery mechanisms.
Muna Alariqi, Mohamed Ramadan, Lu Yu, Fengjiao Hui, Amjad Hussain, Xiaofeng Zhou, Yu Yu, Xianlong Zhang, Shuangxia Jin   +8 more
wiley   +1 more source

Prognostic value of nucleotide excision repair and translesion DNA synthesis proteins in muscle-infiltrating bladder carcinoma. [PDF]

BMC Cancer
Palacka P, Holíčková A, Roška J, Makovický P, Vallová M, Biró C, Órásová E, Obertová J, Mardiak J, Ward TA, Kajo K, Chovanec M.   +11 more
europepmc   +1 more source

Sequential Assembly of the Nucleotide Excision Repair Factors In Vivo [PDF]

, 2001
Marcel Volker, Martijn J. Moné, Parimal Karmakar, Anneke van Hoffen, Wouter Schul, Wim Vermeulen, Jan H.J. Hoeijmakers, Roel van Driel, A.A. van Zeeland, Leon H.F. Mullenders   +9 more
openalex   +1 more source

Transcription-coupled nucleotide excision repair factors promote R-loop-induced genome instability.

Molecules and Cells, 2014
J. Sollier, C. Stork, María L. García-Rubio, R. Paulsen, A. Aguilera, Karlene A. Cimprich   +5 more
semanticscholar   +1 more source