Results 251 to 260 of about 127,063 (412)

The developmental trajectories of the behavioral phenotype and neuropsychiatric functioning in Cornelia de Lange and Rubinstein Taybi syndromes: A longitudinal study

American Journal of Medical Genetics Part A, Volume 191, Issue 2, Page 424-436, February 2023., 2023
Abstract Several changes in the behavioral phenotype arise with the growth of children affected by Cornelia de Lange Syndrome (CdLS) and Rubinstein‐Taybi Syndrome (RSTS). However, previous research relied on a cross‐sectional study design turning into age‐related comparisons of different syndromic cohorts to explore age‐dependent changes.
Paola Francesca Ajmone, Ludovica Giani, Beatrice Allegri, Giovanni Michelini, Francesca Dall'Ara, Claudia Rigamonti, Federico Monti, Paola Giovanna Vizziello, Angelo Selicorni, Donatella Milani, Simona Scaini, Antonella Costantino   +11 more
wiley   +1 more source

TGFβ signaling links early life endocrine-disrupting chemicals exposure to suppression of nucleotide excision repair in rat myometrial stem cells. [PDF]

Cell Mol Life Sci, 2023
Bariani MV, Cui YH, Ali M, Bai T, Grimm SL, Coarfa C, Walker CL, He YY, Yang Q, Al-Hendy A.   +9 more
europepmc   +1 more source

Inhibiting the Histone Demethylase Kdm4a Restrains Cardiac Fibrosis After Myocardial Infarction by Promoting Autophagy in Premature Senescent Fibroblasts

Advanced Science, EarlyView.
Kdm4a downregulation restrains excessive cardiac interstitial fibrosis and remodeling by depressing the premature senescence of fibroblasts in the advanced stage after MI but does not affect early ventricular rupture. It verified that Kdm4a downregulation promotes autophagy in premature senescent fibroblasts by increasing the H3K9m3 modification of the
Ming Jin, Chuling Li, Zhaoyi Wu, Zhenquan Tang, Jingfang Xie, Guoquan Wei, Zhiwen Yang, Senlin Huang, Yijin Chen, Xinzhong Li, Yanmei Chen, Wangjun Liao, Yulin Liao, Guojun Chen, Hao Zheng, Jianping Bin   +15 more
wiley   +1 more source

A pooled analysis of host factors that affect nucleotide excision repair in humans. [PDF]

Mutagenesis
Zheng C, Shaposhnikov S, Collins A, Brunborg G, Azqueta A, Langie SAS, Dusinska M, Slyskova J, Vodicka P, van Schooten FJ, Bonassi S, Milic M, Orlow I, Godschalk R.   +13 more
europepmc   +1 more source

Mutational analysis of the human nucleotide excision repair gene ERCC1

, 1996
Anneke M. Sijbers
openalex   +1 more source

Triple-Helix Formation Induces Recombination in Mammalian Cells via a Nucleotide Excision Repair-Dependent Pathway [PDF]

, 2000
A. Fawad Faruqi, Hirock J. Datta, Dana Carroll, Michael M. Seidman, Peter M. Glazer   +4 more
openalex   +1 more source

NUCLEOTIDE EXCISION REPAIR OF DAMAGED DNA

Cold Spring Harbor Symposia on Quantitative Biology, 1979
L. Grossman, S. Riazuddin, William A. Haseltine, C. Lindan   +3 more
openaire   +3 more sources

MeCP2 Lactylation Protects against Ischemic Brain Injury by Transcriptionally Regulating Neuronal Apoptosis

Advanced Science, EarlyView.
MeCP2 lactylation protects against ischemic stroke by reducing brain infarct volume and improving neurological outcomes. Lactylation at K210/K249 exerts neuroprotective effects by repressing the transcription of apoptosis‐associated genes, including Pdcd4 and Pla2g6. HDAC3 and p300 serve as key regulatory enzymes for MeCP2 lactylation following stroke.
Min Sun, Yuxin Zhang, Rui Mao, Yan Chen, Pinyi Liu, Lei Ye, Siyi Xu, Junqiu Jia, Shu Shu, Huiya Li, Yanping Yin, Shengnan Xia, Yanting Chen, Yun Xu   +13 more
wiley   +1 more source

CARM1/PRMT4 facilitates XPF-ERCC1 heterodimer assembly and maintains nucleotide excision repair activity. [PDF]

Nucleic Acids Res
Niida H, Ito M, Iijima K, Motegi A, Ogihara R, Akiyama H, Uchida C, Sakai S, Ohhata T, Hatano A, Hirose M, Ogura A, Matsumoto M, McDonald NQ, Kitagawa M.   +14 more
europepmc   +1 more source

Mechanism of action of nucleotide excision repair machinery. [PDF]

Biochem Soc Trans, 2022
D'Souza A, Blee AM, Chazin WJ.
europepmc   +1 more source