Results 281 to 290 of about 1,102,607 (331)
The role of Transcription Factor IIH complex in nucleotide excision repair. [PDF]
Environ Mol MutagenHoag A, Duan M, Mao P.
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Interplay of the Tfb1 pleckstrin homology domain with Rad2 and Rad4 in transcription coupled and global genomic nucleotide excision repair. [PDF]
Nucleic Acids ResGong W, Holmberg H, Lu C, Huang M, Li S.
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At the core of nucleotide excision repair.
Current Opinion in Structural Biology, 2023Nucleotide excision repair (NER) is unique in its ability to identify and remove vastly different lesions from DNA. Recent advances in the structural characterization of complexes involved in detection, verification, and excision of damaged DNA have ...
J. Kuper, C. Kisker
semanticscholar +3 more sources
Understanding nucleotide excision repair and its roles in cancer and ageing
Nature Reviews Molecular Cell Biology, 2014Jurgen A Marteijn +2 more
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Nucleotide excision repair in yeast
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 2000In nucleotide excision repair (NER) in eukaryotes, DNA is incised on both sides of the lesion, resulting in the removal of a fragment approximately 25-30 nucleotides long. This is followed by repair synthesis and ligation. The proteins encoded by the various yeast NER genes have been purified, and the incision reaction reconstituted in vitro.
Satya Prakash, Louise Prakash
exaly +3 more sources
Heterogeneity and overlaps in nucleotide excision repair disorders
Clinical Genetics, 2020Nucleotide excision repair (NER) is an essential DNA repair pathway devoted to the removal of bulky lesions such as photoproducts induced by the ultraviolet (UV) component of solar radiation.
Debora Ferri, D. Orioli, Elena Botta
semanticscholar +1 more source
Photochemistry and Photobiology, 1993
Abstract— Nucleotide excision repair is the major DNA repair mechanism in all species tested. This repair system is the sole mechanism for removing bulky adducts from DNA, but it repairs essentially all DNA lesions, and thus, in addition to its main function, it plays a back‐up role for other repair systems.
A, Sancar, M S, Tang
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Abstract— Nucleotide excision repair is the major DNA repair mechanism in all species tested. This repair system is the sole mechanism for removing bulky adducts from DNA, but it repairs essentially all DNA lesions, and thus, in addition to its main function, it plays a back‐up role for other repair systems.
A, Sancar, M S, Tang
openaire +2 more sources
2005
Publisher Summary DNA damage is a common occurrence that compromises the functional integrity of DNA. It is not surprising then that cells have multiple mechanisms for coping with DNA damage, including those introduced by sunlight and other environmental agents.
Joyce T, Reardon, Aziz, Sancar
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Publisher Summary DNA damage is a common occurrence that compromises the functional integrity of DNA. It is not surprising then that cells have multiple mechanisms for coping with DNA damage, including those introduced by sunlight and other environmental agents.
Joyce T, Reardon, Aziz, Sancar
openaire +3 more sources
Nucleotide excision repair and cancer
Journal of Molecular Histology, 2006Nucleotide excision repair (NER) is the most versatile and best studied DNA repair system in humans. NER can repair a variety of bulky DNA damages including UV-light induced DNA photoproducts. NER consists of a multistep process in which the DNA lesion is recognized and demarcated by DNA unwinding.
Diana, Leibeling +2 more
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