Results 101 to 110 of about 878,332 (327)
BiomedicinesAdenine nucleotides play a critical role in maintaining essential functions of red blood cells (RBCs), including energy metabolism, redox status, shape fluctuations and RBC-dependent endothelial and microvascular functions.
Marzena Romanowska-Kocejko +9 more
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ROLE OF PURINERGIC RECEPTORS IN IMMUNE RESPONSE
Журнал микробиологии, эпидемиологии и иммунобиологии, 2016 Purine receptors are located on immune and somatic cells of animal and human organisms. Summation of signals from purine and TOLL-like receptors takes place on the level of inflammasome formation and results in summation of the first and second signals ...
I. B. Semenova
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The Action of 5-Ethyl-5-isoamylbarbiturate (Amytal) on the Oxidation of Reduced Diphosphopyridine Nucleotide (DPNH) in Rat Liver Mitochondria. [PDF]
, 1955 Lars Ernster +3 more
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BioTechnologia, 2015 The object of the invention are 1) nucleotide analogues, 2) antiviral pro-nucleotides, 3) a use of nucleotide analogues and pharmaceutical composition, 4) a phosphorylating agent for synthesis of nucleotide analogue, and 5) a method of synthesis of nucleotide analogues.
Agnieszka Szymanska-Michalak +7 more
openaire +2 more sources
Molecular Oncology, EarlyView.In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim +11 more
wiley +1 more source
Quantum Requirement for Phosphopyridine Nucleotide Reduction in Photosynthesis. [PDF]
, 1959 L.N.M. Duysens, J. Amesz
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Molecular Oncology, EarlyView.Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh +5 more
wiley +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
THE ROLE OF NUCLEOTIDE SUBSTANSES AND NO-SYNTHASE IN THE IMMUNE PROTECTION OF THE ORGANISM
Разработка и регистрация лекарственных средств, 2019 The present article describes the biochemical mechanisms and the possibility of nucleotides and nucleosides substances naturally produced (i.e. Saccharomyces cerevisiae and others) medicine application in field of correction of pathologically altered ...
V. S. Orlova +3 more
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