Results 131 to 140 of about 588,819 (292)

Energy Metabolism of Rickettsia typhi : Pools of Adenine Nucleotides and Energy Charge in the Presence and Absence of Glutamate [PDF]

, 1978
Jim C. Williams, Emilio Weiss
openalex   +1 more source

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

A 68-Nucleotide Sequence within the 3′ Noncoding Region of Simian Hemorrhagic Fever Virus Negative-Strand RNA Binds to Four MA104 Cell Proteins [PDF]

, 1998
You-Kyung Hwang, Margo A. Brinton
openalex   +1 more source

Biomimetic Copper‐Doped Nano‐Aluminum Adjuvant Potentiates Therapy in Chemoresistant Acute Myeloid Leukemia

Advanced Healthcare Materials, EarlyView.
We developed a novel copper‐doped aluminum nano‐adjuvant (CuNA) to overcome cytarabine resistance in acute myeloid leukemia (AML). CuNA effectively sensitizes drug‐resistant AML cells to cytarabine by inducing mitochondrial dysfunction and inhibiting HMGCR/GPX4 to amplify ferroptosis.
Chao He, Lingxiao Zhang, Yue Xiong, Yu Wang, Yuqing Zeng, Dandan Su, Ran Wang, Ying Li, Hongbo Chen, Fang Cheng, Zhi Ping Xu   +10 more
wiley   +1 more source

Skin‐Interfaced Therapeutic Patches for Wound Fluid Management and Transdermal Drug Delivery

Advanced Healthcare Materials, EarlyView.
This study presents an integrated skin‐interfaced device combining microfluidics, hydrogel film technology, flexible electronics, and iontophoresis‐based transdermal delivery of PDRN to enhance wound healing. The device effectively manages wound fluid, maintains optimal moisture, and non‐invasively delivers therapeutic drugs.
Dongjun Han, Donghyun Kim, Haram Lee, Dong‐Wook Park, Sung Soo Kwak, Joohee Kim   +5 more
wiley   +1 more source

Nucleotide [PDF]

, 2019
openaire   +2 more sources

2'-hydroxyl modification improves enzymatic and thermal stability of mRNA. [PDF]

Mol Ther Nucleic Acids
Uchida S.
europepmc   +1 more source

Single-nucleotide promoter polymorphism of angiotensin II type 1 receptor gene AGTR1 affects to sepsis course and outcome in patients with diabetes

, 2022
А.Г. Чумаченко, В.М. Писарев, Р.А. Черпаков, Е.К. Григорьев   +3 more
openalex   +1 more source

From RNA to DNA: How Cargo Identity Reprograms Lipid Nanoparticle Architecture and Function

Advanced Healthcare Materials, EarlyView.
The evolution of lipid nanoparticles (LNPs) spans from RNA‐LNPs, used in mRNA vaccines, to DNA‐LNPs, ideal for gene therapies. Emerging bionano architectures, decorated with DNA and plasma proteins, pave the way for advanced DNA‐based therapies that are more stable, targeted, and customizable.
Erica Quagliarini, Daniela Pozzi, Giulio Caracciolo   +2 more
wiley   +1 more source

Better data for better predictions: data curation improves deep learning for sgRNA/Cas9 prediction. [PDF]

PeerJ
Browne TS, Edgell DR, Gloor GB.
europepmc   +1 more source